Protein Alignment Ubx and En1

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_034263.2
• Gene: En1 / 13798
• MGIID: 95389
• Length: 401
• Species: Mus musculus
• Alignment Length: 276
• Identity: 69/276 - (25%)
• Similarity: 96/276 - (34%)
• Gaps: 71/276 - (25%)

  Fly   109 SNGGGGGGGGGGGGGA----GGTGGAGNANGGNAANANGQNNPAGGMPVRPSA-----CTPDSRV 164
            ::...|||...|||..    .|..|||             .:|...:..|.|.     |.||:..
Mouse   133 ASAAAGGGAAAGGGSRVERDRGQTGAG-------------RDPVHSLGTRASGAASLLCAPDANC 184

  Fly   165 GGYLDTSGGSPVS--HRGGSAGGNVSVSGGNGNAGGVQSGVGVAGAGTAWNANCTISGAAAQTAA 227
            |   ...|..|.:  ..|.|..||.:.:..   |....:...||.|..|.:......|.:...|.
Mouse   185 G---PPDGSQPATAVSAGASKAGNPAAAAA---AAAAAAAAAVAAAAAAASKPSDSGGGSGGNAG 243

  Fly   228 ASSLHQASNHTFYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWL--- 289
            :.....|......|.:.:.|.....|.             :.||       |....:.|.|:
Mouse   244 SPGAQGAKFPEHNPAILLMGSANGGPV-------------VKTD-------SQQPLVWPAWVYCT 288

  Fly   290 -----GTNGLR-------------RRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTE 336
                 .::|.|             :|.|..:|..|...|:.||..|.|:|.:||..:|..|.|.|
Mouse   289 RYSDRPSSGPRTRKLKKKKNEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNE 353

  Fly   337 RQIKIWFQNRRMKLKK 352
            .||||||||:|.|:||
Mouse   354 SQIKIWFQNKRAKIKK 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	26/55 (47%)
En1	NP_034263.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..102
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..167		11/41 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	229..253		3/23 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	293..315		2/21 (10%)
		Homeodomain	314..369	CDD:459649	26/54 (48%)
		Engrail_1_C_sig	370..400	CDD:431338	69/276 (25%)