DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ubx and Dbx1

DIOPT Version :10

Sequence 1:NP_536752.1 Gene:Ubx / 42034 FlyBaseID:FBgn0003944 Length:389 Species:Drosophila melanogaster
Sequence 2:NP_001005232.1 Gene:Dbx1 / 13172 MGIID:94867 Length:335 Species:Mus musculus


Alignment Length:247 Identity:45/247 - (18%)
Similarity:97/247 - (39%) Gaps:78/247 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 LNHSWYIYKLIL--------LTNLAFVL------NVVYSTLVVIG--YKSKTIKEVVDFMHFTAM 78
            :::|.|...:||        :..|.||:      .::.:.|.:||  ||.|::.|          
Mouse     1 MDNSTYFTTVILTGYIDIGDIKYLCFVVLILLFAAIIVANLFIIGIIYKEKSLHE---------- 55

  Fly    79 FPVAVILCGM-------FWGFYVYDSDLVMPAWVAEIVPSWLNHIN----HTYL------IVFIL 126
             |:.|.||.:       .:..:.:....::.:...| ||..:.|..    ::|.      :..:.
Mouse    56 -PMYVFLCSLCANQLCGSFALFPFVLGNMLRSKTPE-VPLTVCHAQIFALYSYAQVEFCNLAMMS 118

  Fly   127 LDSY--------YHKRDAPSNSTS-----WMISVVYVTFYFIIVLGVKY----YNRMWV--YPVL 172
            .|.|        ||:..:|:.:.:     |.:.::.::|.|.:.:.:|:    .:::|.  |.::
Mouse   119 YDRYVAICHPLEYHRIMSPARTMTLIALGWSLEIMILSFSFSVNVQLKFCGNVLDKVWCDQYMLV 183

  Fly   173 QSFSID------LFVISYILSV-----VIFFI---LLKAACKLNRQFHKSIL 210
            :....|      :.:....|::     :|||.   :|:...|..||..|..|
Mouse   184 KLACSDTTPNNIIGITGIPLAIGPPLLIIFFSYAKILRVCLKFTRQKAKKSL 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UbxNP_536752.1 Homeodomain 296..352 CDD:459649
Dbx1NP_001005232.1 PRK12323 <49..182 CDD:481241 23/144 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 58..102 7/44 (16%)
Homeodomain 184..238 CDD:459649 11/52 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 240..335
Blue background indicates that the domain is not in the aligned region.

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