Protein Alignment Ubx and Cdx1

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_034010.3
• Gene: Cdx1 / 12590
• MGIID: 88360
• Length: 268
• Species: Mus musculus
• Alignment Length: 152
• Identity: 53/152 - (34%)
• Similarity: 69/152 - (45%)
• Gaps: 44/152 - (28%)

  Fly   220 GAAAQT---AAASSLHQASNHTFYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLA 281
            |..||:   ..|.|...|...|.|.||               |..:...||             .
Mouse   110 GILAQSLGAPGAPSSPGAPRRTPYEWM---------------RRSVAAAGG-------------G 146

  Fly   282 GSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNR 346
            ||      |....:.:.|..||.:|.||||||||.:.|:|.||:.|:|..|.|||||:|||||||
Mouse   147 GS------GKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNR 205

  Fly   347 RMKLKKEIQAIKELNEQEKQAQ 368
            |.|.:|       :|::::|.|
Mouse   206 RAKERK-------VNKKKQQQQ 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	33/55 (60%)
Cdx1	NP_034010.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		16/75 (21%)
		Caudal_act	13..140	CDD:461413	11/44 (25%)
		Homeodomain	156..211	CDD:459649	33/54 (61%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	157..178		12/20 (60%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	196..207		9/10 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..268		4/19 (21%)