Protein Alignment Ubx and DBX1

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_001025036.2
• Gene: DBX1 / 120237
• HGNCID: 33185
• Length: 343
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 60/236 - (25%)
• Similarity: 86/236 - (36%)
• Gaps: 67/236 - (28%)

  Fly   147 PAGGM-PVR---PSACTPDSRVGGYLDTSGGSPVSHRGGSAGGNVSVSGGNGNAGGVQSGVGVAG 207
            |...| |.|   |:|.|..    |..|.....|.|.||||.                .:....|.
Human    59 PTASMSPPRQGAPTALTDT----GASDLGSPGPGSRRGGSP----------------PTAFSPAS 103

  Fly   208 AGT--AWNANCTISGAAAQTAAASSLHQASNHTF-YPWMAIAGECPEDPTKSKIRSDLTQYGGIS 269
            ..|  .:..|..:|.......:.:.|......|| :|:.       |...:..|||.
Human   104 ETTFLKFGVNAILSSGPRTETSPALLQSVPPKTFAFPYF-------EGSFQPFIRSS-------- 153

  Fly   270 TDMGKRYSESLAGSLLP-----DW-LGTNGLRRRG---RQTYTRYQTLELEKEFHTNHYLTRRRR 325
                  |..: :.|::|     .| |...|..|||   |..::..|...|||.|....|:::..|
Human   154 ------YFPA-SSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDR 211

  Fly   326 IEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKELNEQEKQ 366
            .::|..|.|.:.|:||||||||||.:         |.:|::
Human   212 KKLAAKLGLKDSQVKIWFQNRRMKWR---------NSKERE 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	25/58 (43%)
DBX1	NP_001025036.2	PRK12323	<49..182	CDD:481241	35/164 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..100		15/60 (25%)
		Homeodomain	184..238	CDD:459649	22/62 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..343		1/4 (25%)