Protein Alignment Ubx and CDX4

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_005184.1
• Gene: CDX4 / 1046
• HGNCID: 1808
• Length: 284
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 86/279 - (30%)
• Similarity: 112/279 - (40%)
• Gaps: 91/279 - (32%)

  Fly   117 GGGGGGGAGGTGGAGN-ANGGNAANANGQNNPA----GGMPVRPSACTPDSRVG----------- 165
            ||.|..|.|||||.|: ....|.|.|     ||    .|.|..||.......:|
Human    22 GGDGTAGTGGTGGGGSPMPASNFAAA-----PAFSHYMGYPHMPSMDPHWPSLGVWGSPYSPPRE 81

  Fly   166 ------GYLDTSGGSPVSHRGGSAGGNVSVSGGN-GNAGGVQSGVGVAG-AGTAWNANCTISGAA 222
                  |...|.|..||:....|.....|....| |..||..||..:.| ||          |:.
Human    82 DWSVYPGPSSTMGTVPVNDVTSSPAAFCSTDYSNLGPVGGGTSGSSLPGQAG----------GSL 136

  Fly   223 AQT---AAASSLHQASNHTFYPWM----AIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESL 280
            ..|   ||.:|....|.|:.|.||    .:.|:     |::|                ::|
Human   137 VPTDAGAAKASSPSRSRHSPYAWMRKTVQVTGK-----TRTK----------------EKY---- 176

  Fly   281 AGSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQN 345
                              |..||.:|.||||||||.|.|:|.:|:.|:|..|.|:|||:||||||
Human   177 ------------------RVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQN 223

  Fly   346 RRMKLKKEIQAIKELNEQE 364
            ||.|.:|.|:  |::::.|
Human   224 RRAKERKMIK--KKISQFE 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	32/55 (58%)
CDX4	NP_005184.1	Caudal_act	13..170	CDD:461413	47/167 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..40		10/17 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..155		13/44 (30%)
		Homeodomain	175..230	CDD:459649	33/76 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..259		1/3 (33%)