Protein Alignment Ubx and Hoxa1

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_037207.2
• Gene: Hoxa1 / 103690132
• RGDID: 11414885
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 420
• Identity: 99/420 - (23%)
• Similarity: 151/420 - (35%)
• Gaps: 148/420 - (35%)

  Fly     1 MNSYFEQ---ASG--------FYGHPH-----QATGMAMGSGGHHDQTASAAAAAYRGFPLSLGM 49
            |||:.|.   .||        .|...|     |:..::..|.|..|:....     ||..::
  Rat     6 MNSFLEYPILGSGDSGTCSARVYSSDHGITTFQSCAVSANSCGGDDRFLGG-----RGVQIT--- 62

  Fly    50 SPYANHHLQRTTQDSPYDAS-------ITAACNKIYG--DGAGAYKQDCLNIKADAVNGYKDIWN 105
            ||:.:||.....|.:.|..|       ..::|...||  :.:..|....||.:||...||
  Rat    63 SPHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGAQNFSAPYGPYGLNQEADVSGGY----- 122

  Fly   106 TGGSNGGGGGGGGGGGGGAGGTGGAGNANGGNAANANGQNNPAGGMPVRPSACTPDSRVGGYLDT 170
                                                              ..|.|....|..
  Rat   123 --------------------------------------------------PPCAPAVYSGNL--- 134

  Fly   171 SGGSPV----SHRGGSAGGNVSVSGGNGNAGGVQSGVGVAGAGTA---WNANCTISGAAAQTAAA 228
              .||:    .|..|.|||.|      |:...:....|......|   :|.:.:...|:.|.|..
  Rat   135 --SSPMVQHHHHHQGYAGGTV------GSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACR 191

  Fly   229 SSLHQASN--HTFYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGT 291
            |...:.|:  .|| .||.:    ..:|.|:   ..:.:||.:..               |:.:.|
  Rat   192 SPASETSSPAQTF-DWMKV----KRNPPKT---GKVGEYGYVGQ---------------PNAVRT 233

  Fly   292 NGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKK-EIQ 355
            |         :|..|..|||||||.|.||||.||:|:|.:|.|.|.|:||||||||||.|| |.:
  Rat   234 N---------FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 289

  Fly   356 AIKEL-------NEQEKQAQAQKAAAAAAA 378
            .:..:       ::::.:..::|::::.:|
  Rat   290 GLLPISPATPPGSDEKTEESSEKSSSSPSA 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	32/55 (58%)
Hoxa1	NP_037207.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	61..82		6/23 (26%)
		Interaction with OGT. /evidence=ECO:0000250|UniProtKB:P09022	74..202		33/193 (17%)
		COG5576	175..>285	CDD:227863	49/141 (35%)
		Antp-type hexapeptide	203..208		3/5 (60%)
		Homeodomain	232..285	CDD:459649	34/61 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	280..334		8/40 (20%)