DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubx and hoxb8

DIOPT Version :9

Sequence 1:	NP_536752.1	Gene:	Ubx / 42034	FlyBaseID:	FBgn0003944	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	XP_002938067.1	Gene:	hoxb8 / 100493882	XenbaseID:	XB-GENE-990961	Length:	243	Species:	Xenopus tropicalis

Alignment Length:	221	Identity:	83/221 - (37%)
Similarity:	105/221 - (47%)	Gaps:	45/221 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 GYLDTSGGSPVSHRGGSAGGNVSVSGGNGNAGGVQSGVGVAGAGTAWNANCTISGAAAQTAAASS 230
            |:....||.|....|.||||...      :.|.:|.         .::...::|....|....:.
Frog    27 GFAQDLGGRPTVVYGASAGGTFQ------HPGQIQD---------FYHGTPSLSSPTYQQNPCAV 76

  Fly   231 LHQASNHTFYPWMAIAGECPEDPTK-----SKIRSDLTQYGG---ISTDMGKRYSESLAGSLLP- 286
            .......:||.:         ||.:     |...::|.||..   .|..:|:. :||...|..|
Frog    77 TCHGDPGSFYGY---------DPLQRQSLFSSQDTELVQYSECKLASAGLGEE-AESSEQSPSPT 131

  Fly   287 ---DWLGTNGL--RRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNR 346
               .|:.....  ||||||||:|||||||||||..|.||||:||||::|||.|||||:|||||||
Frog   132 QLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNR 196

  Fly   347 RMKLKKEIQAIK------ELNEQEKQ 366
            |||.|||....|      |..|.|||
Frog   197 RMKWKKENNKDKFPSSKCEQEELEKQ 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeobox	299..352	CDD:395001	42/52 (81%)
hoxb8	XP_002938067.1	Homeobox	149..202	CDD:365835	42/52 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910