DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubx and hoxc3

DIOPT Version :9

Sequence 1:	NP_536752.1	Gene:	Ubx / 42034	FlyBaseID:	FBgn0003944	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	XP_002936696.1	Gene:	hoxc3 / 100190990	XenbaseID:	XB-GENE-5997986	Length:	394	Species:	Xenopus tropicalis

Alignment Length:	238	Identity:	71/238 - (29%)
Similarity:	98/238 - (41%)	Gaps:	41/238 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 GGTGGAGNANGGNAANANGQNNPAGGMPVRPSACTPDSRVGGYLDTSGGSPVSHRG-GSAGG--- 185
            ||.|..||    |.....||.:.......:|..|.|.       ||:.|| .||:| .|..|
Frog    16 GGCGFQGN----NGMGYLGQQDYPSEDDYQPPFCLPP-------DTANGS-ASHKGEHSIKGIDF 68

  Fly   186 ---NVSVSGGNGNAGGVQSGVGVAGAGTAWNANCTISGAAAQTAAASSLHQASN--HTFYPWMAI 245
               .||.......:....|.:..:.:..:..:..:....::...:.:...:.||  ...:|||
Frog    69 HLSEVSEQAQQPKSPNSDSPLPKSASTQSCTSKKSTGPVSSDVTSPNKKSKGSNMPKQIFPWM-- 131

  Fly   246 AGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTLEL 310
                .|....||.:.........:..:...:..|.:              :|.|..||..|.:||
Frog   132 ----KETRQNSKQKKQAPPPADDAPAVDSSFLSSAS--------------KRARTAYTNSQLVEL 178

  Fly   311 EKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKE 353
            |||||.|.||.|.||:|||..|.|:||||||||||||||.||:
Frog   179 EKEFHFNRYLCRPRRLEMAKLLNLSERQIKIWFQNRRMKFKKD 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeobox	299..352	CDD:395001	36/52 (69%)
hoxc3	XP_002936696.1	Homeobox	167..220	CDD:395001	36/52 (69%)
hoxc3	XP_002936696.1	DUF4074	335..392	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910