DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubx and hoxa3

DIOPT Version :9

Sequence 1:	NP_536752.1	Gene:	Ubx / 42034	FlyBaseID:	FBgn0003944	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001120901.1	Gene:	hoxa3 / 100151729	XenbaseID:	XB-GENE-482267	Length:	406	Species:	Xenopus tropicalis

Alignment Length:	173	Identity:	61/173 - (35%)
Similarity:	85/173 - (49%)	Gaps:	25/173 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 TISGAAAQTAAASSLHQAS-NHTFYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESL 280
            |.:.|.|.:..|:|:...: :...:|||           |...::...|..|.|:.     .||.
Frog   104 TSNAATASSNKATSITSPTMSKQIFPWM-----------KESRQNTKQQKAGSSSS-----GESC 152

  Fly   281 AGSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQN 345
            ||...|....::   :|.|..||..|.:|||||||.|.||.|.||:|||:.|.||||||||||||
Frog   153 AGDKSPPGQSSS---KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 214

  Fly   346 RRMKLKKEIQAIKELNEQEKQAQAQKAAAAAAAAAAVQGGHLD 388
            ||||.||:.:....:.....|:..:......:.     ||:|:
Frog   215 RRMKYKKDQKGKSMMTSSGGQSPCRSPVPTPSV-----GGYLN 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeobox	299..352	CDD:395001	37/52 (71%)
hoxa3	NP_001120901.1	Homeobox	168..221	CDD:395001	37/52 (71%)
hoxa3	NP_001120901.1	DUF4074	344..404	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910