DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and c1s.2

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_001107921.2	Gene:	c1s.2 / 793504	ZFINID:	ZDB-GENE-030131-4645	Length:	458	Species:	Danio rerio

Alignment Length:	351	Identity:	83/351 - (23%)
Similarity:	131/351 - (37%)	Gaps:	91/351 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   317 PPGTEVKFV---CSTGFKTLSPLPEMRCMKGGYW--NRGRQ------RCEQDCGQLATPIKQFSS 370
            ||.|.:|.:   |.:.|..|.......|...|.|  ..|.:      :||..||   ..::..|:
Zfish   154 PPTTYLKQISLKCKSEFYQLDKKGNFTCNAEGNWVSENGEKLTKIFPKCEPVCG---INMEDLSA 215

  Fly   371 ----GGYTINNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDL-VITAAHCVYDEGTR-------L 423
                ||....:..:||.    :.|.....    |.:.|..|. .:|||..|.....|       :
Zfish   216 GRVFGGKPARSGEIPWQ----LLHKSSPR----GSATLISDYWALTAASLVDGNENRNMSWLGGI 272

  Fly   424 PYSYDTFRVIAAKFYRNYGETTPEEKRRDVRLIEIAPGYK-----GRTENYYQDLALLTLDEPFE 483
            ..:.||..|        :.||   ||      |.|.|.||     ||..::..|:||:.:.....
Zfish   273 VNAQDTNAV--------FMET---EK------IIIHPNYKKVDKDGRQSDFNNDIALIKMSAMVP 320

  Fly   484 LSHVIRPICVTFASFAEKESVTDDVQGKFAGWNIENKHELQFVPAVSKSNSVCRRNLRDIQADKF 548
            |...|||:|:...:   .|:|.:.:.|..:|:.:..:       .|||   :.|.....:.:.|.
Zfish   321 LGPNIRPVCLPKKT---DEAVKEGMMGTVSGFGVYGR-------TVSK---LLRYGHVHVYSLKS 372

  Fly   549 CI----------FTQGKSL----ACQGDSGGGFTSELPTNAFSTWNTARHFLFGVISNAPNADQC 599
            |:          |..|..:    :|.|||||...  .|.....| ...|:.:.|::|..|   .|
Zfish   373 CVSGDLPVSDNMFCAGDDVHGIDSCSGDSGGPLF--FPMLGDGT-EEHRYVVKGIVSWGP---IC 431

  Fly   600 AHSLT--VMTNIQHFEDMILNAMNRS 623
            |.::|  ..|.:|::.|.|...|.::
Zfish   432 AKTITKGYYTKVQNYLDWIEETMAKN 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512	11/47 (23%)
		Tryp_SPc	371..616	CDD:214473	65/273 (24%)
		Tryp_SPc	371..591	CDD:304450	57/246 (23%)
c1s.2	NP_001107921.2	CUB	25..133	CDD:238001
c1s.2	NP_001107921.2	Tryp_SPc	217..450	CDD:214473	65/276 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000