DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and CG34409

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_001097728.2	Gene:	CG34409 / 5740854	FlyBaseID:	FBgn0085438	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	455	Identity:	91/455 - (20%)
Similarity:	163/455 - (35%)	Gaps:	128/455 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 EESSYCAKNK------------WSTSTIPKCVKYCSTAGEFDGYSTKALCTHN----GQQVECRK 313
            :|||:...::            |..:...|..::..|.|::....|.   .|:    .:|..|.:
  Fly    80 DESSFVKASRKMRFAPPNDRWIWDGADSDKGSRHSHTHGDYLEAETN---LHDYWNFEEQRNCPQ 141

  Fly   314 PFHPPGTEVKFVCSTGF----------KTLSPLP---------EMRCMKGGYWNRGRQRCEQDCG 359
            |..|...:.:|.....|          ..|.|:|         ::|     :..:|.:..:.:..
  Fly   142 PVEPEFFDRRFALGHHFLYHVEHEERDTLLRPVPKDKPIVFPGDLR-----FQRQGEEAIDSNID 201

  Fly   360 Q----------LATPIKQFSSGGYTINNTVVPW----------------------HVGLYVWHNE 392
            |          |||||:...:...|...::.|:                      ..|.:.|...
  Fly   202 QGPPLAPFTTTLATPIETIPASLSTTTASMPPFAQENTQGCGINVESRLLGGDQASAGQFPWLTR 266

  Fly   393 KDYH--------FQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAAKFYRNYGETTPEEK 449
            ..|.        |:|.|||::.:.::||||||.:..:.|..|:       .:.....| .||..
  Fly   267 IAYRNRSSSRISFRCSGSLISSNHIVTAAHCVVNLVSDLELSH-------VRLGSQDG-ATPFA- 322

  Fly   450 RRDVRLIEIAPGYKGRTENYYQDLALLTLDEPFELSHVIRPICVTFASFAEKESVTDDVQGKFAG 514
               :..:.:.|.|.  ...|..|:|||.::   ..:....|||:.|.......:......|..||
  Fly   323 ---IEQVIVHPNYD--QPKYANDIALLRIN---STNGTFTPICLPFNGPITLGNRLIGQIGVAAG 379

  Fly   515 WNI---ENKHEL---------QFV--PAVSKSN-SVCRRNLRD-------IQADKFCIFTQGKSL 557
            |:|   ||...:         :|:  |.|:.:: ::...:|.:       |..:..|  .||..:
  Fly   380 WSIGSTENNSSMDPSNSTAGVRFIRLPIVNTTSCAIAYASLSENFQQPIVITPNHLC--AQGMPM 442

  Fly   558 --ACQGDSGGGFTSELPTNAFSTWNTARHFLFGVISNAPNADQCAHSLTVMTNIQHFEDMILNAM 620
              .|:|||||.|..:..:..|.|  :.|:.:.|:::..|..........|.|.:..|.|.||.::
  Fly   443 NDVCRGDSGGPFMDDGTSGVFGT--SGRYTIIGIVAFGPTLCGVTTIPGVYTLVSSFSDWILRSI 505

Fly 621 620
Fly 506 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056	5/30 (17%)
		Sushi	309..354	CDD:278512	10/63 (16%)
		Tryp_SPc	371..616	CDD:214473	63/298 (21%)
		Tryp_SPc	371..591	CDD:304450	58/273 (21%)
CG34409	NP_001097728.2	CLIP	26..71	CDD:288855
		Tryp_SPc	249..501	CDD:214473	61/272 (22%)
		Tryp_SPc	252..501	CDD:238113	61/269 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437249
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030