DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and Jon99Fii

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_651799.1	Gene:	Jon99Fii / 43621	FlyBaseID:	FBgn0039777	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	61/266 - (22%)
Similarity:	86/266 - (32%)	Gaps:	93/266 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   332 TLSPLPEMRCMKGGYWNRGRQRCEQDCGQLATPIKQFS-----SGGYTINNTVVPWHVGLYVWHN 391
            |..|.||.:.                   :.||:|...     :.||......||:.|||....|
  Fly    15 TAIPTPEQKL-------------------VPTPVKDVKIQGRITNGYPAYEGKVPYIVGLLFSGN 60

  Fly   392 EKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAAKFYRNYGETTPEEKRRDVRLI 456
            .   ::.||||::....|:|||||...               |:....|||.:...:
  Fly    61 G---NWWCGGSIIGNTWVLTAAHCTNG---------------ASGVTINYGASLRNQ-------- 99

  Fly   457 EIAPGYKG-------------RTENYYQDLALLTLDEPFELSHVIRPICVTFASFAEKESVTDDV 508
               |.|..             .:.|.:.|::|:.... .:..|::..:        |..|..|..
  Fly   100 ---PQYTHWVGSGNFVQHHHYNSGNLHNDISLIRTPH-VDFWHLVNKV--------ELPSYNDRY 152

  Fly   509 QGKFAGW------------NIENKHELQFVPAVSKSNSVCRR--NLRDIQADKFCIFTQGKSLAC 559
            | .:|||            .......||.|.....|.|.|.|  :|.|   :..||.|.|....|
  Fly   153 Q-DYAGWWAVASGWGGTYDGSPLPDWLQAVDVQIMSQSDCSRSWSLHD---NMICINTNGGKSTC 213

  Fly   560 QGDSGG 565
            .|||||
  Fly   214 GGDSGG 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512	4/21 (19%)
		Tryp_SPc	371..616	CDD:214473	54/222 (24%)
		Tryp_SPc	371..591	CDD:304450	54/222 (24%)
Jon99Fii	NP_651799.1	Tryp_SPc	37..259	CDD:214473	54/225 (24%)
Jon99Fii	NP_651799.1	Tryp_SPc	38..262	CDD:238113	54/224 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436818
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030