DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and SPE

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_651168.1	Gene:	SPE / 42791	FlyBaseID:	FBgn0039102	Length:	400	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	69/277 - (24%)
Similarity:	99/277 - (35%)	Gaps:	77/277 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 CGQLATPIKQFSSGGYTINNTVV---PWHVGL-YVWHNEKDYHFQCGGSLLTPDLVITAAHCV-- 416
            ||.|      |:...:...||.:   ||.|.| |.....:.|.|.|||:||....|:||.||:
  Fly   127 CGFL------FADRIFGGTNTTLWEFPWMVLLQYKKLFSETYTFNCGGALLNSRYVLTAGHCLAS 185

  Fly   417 --YDEGTRLPYS-----YDTFRVIAAKFYRNYGETTPE------------EKRRDVRLIEIAPG- 461
              .|:...:.:|     :||             .|.|:            .|..|   ||:..|
  Fly   186 RELDKSGAVLHSVRLGEWDT-------------RTDPDCTTQMNGQRICAPKHID---IEVEKGI 234

  Fly   462 ----YKGRTENYYQDLALLTLDEPFELSHVIRPICVTFASFAEKESVTDDVQGKFAGWNI-ENKH 521
                |...:.:...|:||:.|......:..:||||:......:...|  |.....|||.: ||..
  Fly   235 IHEMYAPNSVDQRNDIALVRLKRIVSYTDYVRPICLPTDGLVQNNFV--DYGMDVAGWGLTENMQ 297

  Fly   522 ELQFVPAVSKSNSVCRRNLRDIQADKFCIF---------TQGKSL---ACQGDSGGGFTSELPTN 574
            .    .|:....:|...||...| :|:..|         ..|..|   .|.|||||.....:.|.
  Fly   298 P----SAIKLKITVNVWNLTSCQ-EKYSSFKVKLDDSQMCAGGQLGVDTCGGDSGGPLMVPISTG 357

  Fly   575 AFSTWNTARHFLFGVIS 591
            ....:     ::.||.|
  Fly   358 GRDVF-----YIAGVTS 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512
		Tryp_SPc	371..616	CDD:214473	65/264 (25%)
		Tryp_SPc	371..591	CDD:304450	64/262 (24%)
SPE	NP_651168.1	CLIP	42..94	CDD:314844
SPE	NP_651168.1	Tryp_SPc	135..397	CDD:238113	65/263 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437261
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940