DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and CG16710

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_651167.3	Gene:	CG16710 / 42790	FlyBaseID:	FBgn0039101	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	405	Identity:	95/405 - (23%)
Similarity:	137/405 - (33%)	Gaps:	102/405 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   261 VLEGEESSYCAKNKWSTSTI-PKCVKY--CSTAGEFDGYSTKALCTHNGQQVE--------CRKP 314
            ||..:...|.|::::....: .||:..  |::...|       |..||....|        |  .
  Fly    13 VLHTQLLMYLAESEYPPCNLDEKCISLARCTSLLPF-------LKPHNMTPAEKAVFEDRYC--G 68

  Fly   315 FHPPGTEV---KFVCSTGFKTLSPLPEMRCMKGGYWNRGRQRCEQDCGQLATPIKQFSSGGYTIN 376
            :.|.|.|:   ..:|......:.|..::                  ||.:....:.|  ||....
  Fly    69 YGPKGQELLDRVLICCPNMGHILPNTQI------------------CGPIMPAYRIF--GGEETQ 113

  Fly   377 NTVVPW-------HVGLYVWHNEKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIA 434
            ...:||       |....|| ||: ...:|.|||:|...|:|||||:...|      .|..||
  Fly   114 PNELPWMALILYAHRSRSVW-NER-LVSRCAGSLITNRYVLTAAHCLRITG------LDLRRV-- 168

  Fly   435 AKFYRNYGE------------------TTPEEKRRDVRLIEIAPGYKGRTENYYQDLALLTLDEP 481
                 ..||                  ..||....||.|......|....|..|.|:|||.|..|
  Fly   169 -----RLGEHNILSNPDCVTHINGREHCAPEHLEIDVDLSIKHRHYMVFEERPYNDIALLRLKFP 228

  Fly   482 FELSHVIRPICVTFASFAEKESVTDDVQGKFAGWNIENKHELQFVPAVSKSN----SVCRRNLRD 542
            ...:..|:||||.........|.::. :.:.|||.:.:|.....|...:..|    ..|..:...
  Fly   229 VRYTAQIKPICVQLDYIFSNPSFSNH-KLQIAGWGLSHKQGYSNVLLQAYVNGRNADECSLSEPS 292

  Fly   543 IQADK---FCIFTQGKSLACQGDSGGGFTS--ELPTNAFSTWNTARHFLFGVISNAPNADQCAHS 602
            :..||   .|....|.:..|:|||||...:  |.....|.       :|.|:.|.  ...||.:.
  Fly   293 LGLDKETHICAGNLGGNDTCKGDSGGPLMAIMERGDEEFV-------YLAGITSY--GYSQCGYG 348

  Fly   603 LTVMTNIQHFEDMIL 617
            ....|....|.:.||
  Fly   349 PAAYTKTSKFVEWIL 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056	5/23 (22%)
		Sushi	309..354	CDD:278512	7/55 (13%)
		Tryp_SPc	371..616	CDD:214473	72/278 (26%)
		Tryp_SPc	371..591	CDD:304450	67/253 (26%)
CG16710	NP_651167.3	CLIP	35..84	CDD:288855	12/57 (21%)
		Tryp_SPc	105..362	CDD:214473	73/283 (26%)
		Tryp_SPc	106..362	CDD:238113	73/282 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437225
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030