DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment modSP and CG31219

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_001097837.1	Gene:	CG31219 / 42344	FlyBaseID:	FBgn0051219	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	78/343 - (22%)
Similarity:	112/343 - (32%)	Gaps:	135/343 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   306 GQQVECRKPFHPPGTEVKFVCSTGFKTLSPLPEMRCMKGGYWNRGRQRCEQDCGQLATPIKQFSS 370
            ||::.|    .|||..:            |..|:                  |||..:..:..
  Fly    62 GQRICC----PPPGNRL------------PSTEI------------------CGQSLSTYRMV-- 90

  Fly   371 GGYTINNTVVPWHVGLYVWHNEKDYHFQ--CGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVI 433
            ||........|| :.:.::.|.......  |.|||:....|:|:||||    ..:|      |.:
  Fly    91 GGSEARPNGYPW-MAMLLYLNTTTLEILPFCAGSLINNRYVLTSAHCV----NGIP------RDL 144

  Fly   434 AAKFYRNYGE--------TTPEEKRRD---------VRLIEIA-----PGYKGRTENYYQDLALL 476
            :.|..| .||        ..|:.:.:|         ::|.:|.     .....|...|  |:|||
  Fly   145 SLKSVR-LGEHDITYDPAYNPDCRDQDNQCALPNLEIKLEKIIVHGLFSSISNRNIEY--DIALL 206

  Fly   477 TLDEPFELSHVIRPICVTFASFAEKESVTDDVQGKFAGWNIENKHELQFVPAV------SKSNSV 535
            .|..|......|.|||:....|..|..:      :.|||...|  |.||...:      .:|.:|
  Fly   207 RLKMPVRYRTGIMPICIPKHGFFAKSKL------EIAGWGKTN--EGQFSQVLMHGFIRERSIAV 263

  Fly   536 CRRNLRDIQADKFCIFTQGKSL-----------ACQGDSGG--------------GFTS------ 569
            |        |.:|......:||           .|||||||              |.|:
  Fly   264 C--------ALRFPYLDLNQSLQICAGGYDGVDTCQGDSGGPLMVTMDNSSVYLAGITTYGSKNC 320

  Fly   570 ---ELP-----TNAFSTW 579
               .:|     |:||..|
  Fly   321 GQIGIPGIYTRTSAFLPW 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512	6/44 (14%)
		Tryp_SPc	371..616	CDD:214473	67/278 (24%)
		Tryp_SPc	371..591	CDD:304450	67/278 (24%)
CG31219	NP_001097837.1	Tryp_SPc	88..339	CDD:214473	67/283 (24%)
CG31219	NP_001097837.1	Tryp_SPc	90..342	CDD:238113	67/281 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437213
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030