DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and CG9649

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	348	Identity:	89/348 - (25%)
Similarity:	128/348 - (36%)	Gaps:	95/348 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 QVECRKPFHPPGTEVKFVCSTGF--KTLSPLPEMRCMKGGYWNRGRQRCEQDCGQLATPIKQFSS 370
            |...|...||..|..:   ::.|  :|:..|..: |        ||::..|      ||   |..
  Fly   215 QTSARPSVHPSNTPAQ---ASKFYPQTIGQLSGI-C--------GREKVIQ------TP---FIH 258

  Fly   371 GGYTINNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAA 435
            .|..:....:||...|:. |..:||:|.|||:|::...||:||||.......||
  Fly   259 NGIEVERGQLPWMAALFE-HVGRDYNFLCGGTLISARTVISAAHCFRFGSRNLP----------- 311

  Fly   436 KFYRNYGETTPEEKRRD-------------VRLIEIAPGYKGRTENYY--QDLALLTLDEPFELS 485
                  ||.|.....|:             .||: |...|   ..|.|  .|||||.|....::.
  Fly   312 ------GERTIVSLGRNSLDLFSSGATLGVARLL-IHEQY---NPNVYTDADLALLQLSNHVDIG 366

  Fly   486 HVIRPICVTFASF------AEKESVTDDVQGKFAGWNIENKHELQFVPAVSKSNSV-----CRRN 539
            ..|:|||:...:|      ..|..|        |||..:.|.......|......:     ||.|
  Fly   367 DYIKPICLWNENFLLELPSGHKSYV--------AGWGEDEKGNRNTRLAKMTDTDIITQWECRGN 423

  Fly   540 LRD-----IQADKFCIFTQGKSLACQGDSGGGFTSELPTNAFSTWNTARHFLFGVISNAPN-ADQ 598
            |.:     |.:...|......|..|.||||||    |.......|     .|.||:|.... .::
  Fly   424 LSEENAKFITSHTICASNAQASGPCSGDSGGG----LMLQEQDIW-----MLRGVVSAGQRMTNR 479

  Fly   599 CAHSLTVM-TNIQHFEDMILNAM 620
            |..:|.|: |::....:.:|::|
  Fly   480 CNLTLPVIYTDVAKHIEWLLSSM 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512	10/46 (22%)
		Tryp_SPc	371..616	CDD:214473	72/277 (26%)
		Tryp_SPc	371..591	CDD:304450	67/250 (27%)
CG9649	NP_650343.1	GD_N	29..124	CDD:292649
		Tryp_SPc	257..498	CDD:238113	72/279 (26%)
		Tryp_SPc	259..497	CDD:214473	72/276 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436926
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940