DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and CG13318

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_649831.1	Gene:	CG13318 / 41048	FlyBaseID:	FBgn0037627	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	81/365 - (22%)
Similarity:	121/365 - (33%)	Gaps:	117/365 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 SSYCAKNKWSTSTIP--KCVKYCSTA-----GEFD-------GYSTKALCTHNGQQVECRKPFHP 317
            :|||       ..:|  .|.....||     |:.|       ||.|                  .
  Fly    88 TSYC-------QCVPPGSCANPLPTAPSDGSGQIDIRIVNNGGYPT------------------V 127

  Fly   318 PGTEVKFVCSTGFKTLSPLPEMRCMKGGYWNRGRQRCEQDCGQLATPIKQFSSGGYTINNTVVPW 382
            |.|.....||.|.        :.|.:.|.:..|| |.....|.......|.|.|.|       ||
  Fly   128 PTTSSTLTCSYGL--------VACCQAGSYQCGR-RFPPPPGSTTAAPGQASFGAY-------PW 176

  Fly   383 HVGLYVWHNEKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAAKFYRNYGETTPE 447
            ...|.   ...|.:.. ||:|:|...|:||||.||:.|  |.|    |:|...::  :...|:..
  Fly   177 QAALL---TTADVYLG-GGALITAQHVLTAAHKVYNLG--LTY----FKVRLGEW--DAASTSEP 229

  Fly   448 EKRRDVRLIEIAPGYKGRTENYYQDLALLTLDEPFELS--HVIRPICVTFASFAEKESVTDDVQG 510
            ...:||.:..:.........|...|:|:|.|..|..|:  ..:..:|:...||..:....
  Fly   230 IPAQDVYISNVYVNPSFNPNNLQNDVAILKLSTPVSLTSKSTVGTVCLPTTSFVGQRCWV----- 289

  Fly   511 KFAGWN------------IENKHELQFVPAVSKSNSVCRRNLRDIQADK------------FCIF 551
              |||.            ||.:.::..:|     |:.|:..|   ||.:            .|..
  Fly   290 --AGWGKNDFGATGAYQAIERQVDVPLIP-----NANCQAAL---QATRLGSSFVLSPTSFICAG 344

  Fly   552 TQGKSLACQGDSGGGFTSELPTNAFSTWNTARHFLFGVIS 591
            .:....||.||.|    |.|...:...|     ::.|:::
  Fly   345 GEAGKDACTGDGG----SPLVCTSNGVW-----YVVGLVA 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056	4/18 (22%)
		Sushi	309..354	CDD:278512	9/44 (20%)
		Tryp_SPc	371..616	CDD:214473	56/247 (23%)
		Tryp_SPc	371..591	CDD:304450	56/245 (23%)
CG13318	NP_649831.1	Tryp_SPc	169..402	CDD:238113	57/250 (23%)
CG13318	NP_649831.1	Tryp_SPc	169..399	CDD:214473	57/250 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030