DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and C1rl

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_001002804.2	Gene:	C1rl / 408246	RGDID:	1302936	Length:	488	Species:	Rattus norvegicus

Alignment Length:	422	Identity:	89/422 - (21%)
Similarity:	151/422 - (35%)	Gaps:	105/422 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 TRGTVRFSCKQGYVLEGEESSYCAKNKWSTSTIPKCVKYCSTAGE----FDGYSTKALCT--HNG 306
            ||||             :.:..|.:...|..:.|..:::.|:...    |..:|:|...|  |.|
  Rat   106 TRGT-------------DATRLCGQQGSSLGSPPNQMEFVSSGRSLRLTFRAHSSKNKVTHLHKG 157

  Fly   307 -----QQVECRKP------FHPPGT---EVKFVCSTGFKTLSPLPEMRCMKGGYWNRGRQR---- 353
                 |.:...:|      |..||.   |::..|...:........:.|.....| :.|||
  Rat   158 FLALYQAIAVSQPNGDAEAFTTPGANPPEIQNHCPGPYYKEEQTGTLSCPSSRKW-KDRQRGEEV 221

  Fly   354 --CEQDCGQLATPIKQ----FSSGGYTINNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDLVITA 412
              |...||:...||.:    |.|      :...|   |.:.|......:.:.||:||....::||
  Rat   222 PECVPVCGRPVVPIAENPNTFGS------SRAKP---GNFPWQAFTSIYGRGGGALLGDRWILTA 277

  Fly   413 AHCVYDEGTRLPYSYDTFRVIAAKFYRNYGETTPEE----KRRDVRLIEIAPGYK-GRTENYYQD 472
            ||.::.:.:.......|..|.       .|.|..:|    ....||.:.:.|.|: ..:.|:..|
  Rat   278 AHTIFPKDSIYLRKNKTVNVF-------LGHTDVDELLKLGNHPVRRVVVHPDYRQEESHNFDGD 335

  Fly   473 LALLTLDEPFELSHVIRPICVTFASFAEKESV-TDDVQGKFAGWNIE-----NKHELQFVPAVSK 531
            :|||.|:....|...:.|:|:     .:.|:: ...:.|..:|:.:|     .|.:...:|...:
  Rat   336 IALLELEHRVPLGPSLLPVCL-----PDNETLYHSGLWGYISGFGVEMGWLTTKLKYSKLPVAPR 395

  Fly   532 SNSVCRRNLRDIQA------DKFCIFTQGKSL----ACQGDSGGGFTSELPTNAFSTWN--TARH 584
              ..|...||..|.      :.||:   |:.:    .||||||         :.:..|:  ..|.
  Rat   396 --EACEAWLRQRQRTEVFSDNMFCV---GEEMQVNSVCQGDSG---------SVYVVWDDRALRW 446

  Fly   585 FLFGVISNAPNADQCAHSLTVMTNIQHFEDMI 616
            ...|::|....   |.......|.:..:.|.|
  Rat   447 VATGIVSWGVG---CGKGYGFYTKVLSYVDWI 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056	4/32 (13%)
		Sushi	309..354	CDD:278512	11/59 (19%)
		Tryp_SPc	371..616	CDD:214473	55/267 (21%)
		Tryp_SPc	371..591	CDD:304450	51/242 (21%)
C1rl	NP_001002804.2	CUB	55..164	CDD:238001	14/70 (20%)
C1rl	NP_001002804.2	Tryp_SPc	243..476	CDD:238113	57/271 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910