DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	276	Identity:	72/276 - (26%)
Similarity:	108/276 - (39%)	Gaps:	55/276 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 CG-QLATPIKQFSSGGYTINNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDLVITAAHCVYDEGT 421
            || :..||.....:||........||...|    .:.:.| :||.:|::...:||||||......
  Rat   175 CGRRTITPGGHKVAGGQDAEEGEWPWQASL----QQNNVH-RCGATLISNSWLITAAHCFVRSAN 234

  Fly   422 RLPYSYDTFRVIAAKFYRNYGETTPEEKRRDVRLIEIAPGYKGRTENYYQDLALLTLDEPFELSH 486
            ...:.. :|..:.:|          .:.:|.|:.|.|...|.....|  .|:|::.|..|....:
  Rat   235 PKDWKV-SFGFLLSK----------PQAQRAVKSIVIHENYSYPAHN--NDIAVVRLSSPVLYEN 286

  Fly   487 VIRPICVTFASFAEKESVTDDVQGKFAGW----------NIENKHELQFVPAVSKSNSVCRRNLR 541
            .||..|:..|:  :|.....||  ...||          ||..|..::.:     .|..|.....
  Rat   287 NIRRACLPEAT--QKFPPNSDV--VVTGWGTLKSDGDSPNILQKGRVKII-----DNKTCNSGKA 342

  Fly   542 ---DIQADKFCI-FTQGKSLACQGDSGGGFTSELPTNAFSTWNTARHFLFGVISNAPNADQCA-- 600
               .|.....|. |.:|:..||||||||...||   ::...|     ||.|::|   ..|:||
  Rat   343 YGGVITPGMLCAGFLEGRVDACQGDSGGPLVSE---DSKGIW-----FLAGIVS---WGDECALP 396

  Fly   601 HSLTVMTNIQHFEDMI 616
            :...|.|.:.|:.|.|
  Rat   397 NKPGVYTRVTHYRDWI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512
		Tryp_SPc	371..616	CDD:214473	67/260 (26%)
		Tryp_SPc	371..591	CDD:304450	59/233 (25%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	67/263 (25%)
		Tryp_SPc	187..415	CDD:238113	68/264 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000