DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment modSP and CG10469

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_648025.1	Gene:	CG10469 / 38696	FlyBaseID:	FBgn0035678	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	238	Identity:	59/238 - (24%)
Similarity:	91/238 - (38%)	Gaps:	64/238 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   365 IKQFS------SGGYTINNTV------VPWHVGLYVW-HNEKDYHFQCGGSLLTPDLVITAAHCV 416
            |.|||      :|...|.|..      :|:.|||..: ...||....|||::|:...:||||||:
  Fly     8 IVQFSLVFGQETGSLRIMNGTAAKAKQLPYQVGLLCYFEGSKDEPNMCGGTILSNRWIITAAHCL 72

  Fly   417 YDEGTRL---------PYSYDTFRVIAAKFYRNYGETTPEEKRRDVRLIEIAPGYKGRTENYYQD 472
            .|..:.|         ..|:|...::..:.|      |...|:.|.:.:.             .|
  Fly    73 QDPKSNLWKVLIHVGKVKSFDDKEIVVNRSY------TIVHKKFDRKTVT-------------ND 118

  Fly   473 LALLTLDEPFELSHVIRPICVTFASFAEKESVTDDVQGK---FAGWNIENK----HELQFVPAVS 530
            :||:.|.:....:..|:|        |:..|......|:   .:||.:..|    ..||::.|..
  Fly   119 IALIKLPKKLTFNKYIQP--------AKLPSAKKTYTGRKAIISGWGLTTKQLPSQVLQYIRAPI 175

  Fly   531 KSNSVCRR--------NLRDIQADKFCIFTQGKSLACQGDSGG 565
            .||..|.|        ..:.:..:.|......|.|.|:|||||
  Fly   176 ISNKECERQWNKQLGGKSKKVVHNGFICIDSKKGLPCRGDSGG 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512
		Tryp_SPc	371..616	CDD:214473	55/226 (24%)
		Tryp_SPc	371..591	CDD:304450	55/226 (24%)
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	54/223 (24%)
CG10469	NP_648025.1	Tryp_SPc	24..260	CDD:238113	54/222 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436902
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030