DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment modSP and scaf

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_610180.1	Gene:	scaf / 35505	FlyBaseID:	FBgn0033033	Length:	655	Species:	Drosophila melanogaster

Alignment Length:	664	Identity:	137/664 - (20%)
Similarity:	205/664 - (30%)	Gaps:	218/664 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 FAACDSSQFECDNGSCISQYDVCNGEK--NCPDGSDETALTCVSQRQHCTKPYFQCTY---GACV 83
            |..|...|....:|.|::.|......|  ||    |.....|             |||   ....
  Fly    81 FLKCAPGQQCVRSGQCLNGYFAQQLPKIQNC----DPETTVC-------------CTYRPPPTTT 128

  Fly    84 IGTAGCNGVNECADGSDETRLRCGNEDDIRQHDRRLQGNCKENEF------------KCPSG--I 134
            ..|.....|..||..||     |...|           ||:..|.            :||:.  .
  Fly   129 TTTTTSVPVANCAYDSD-----CVTPD-----------NCRNGEISAINYVKKQGPNRCPAPNIC 177

  Fly   135 CLDKSNFLCDGKDDCADGTGFDESVELCGHMECPAYSFKCGTGGCISGSLSCNGENDCYDGSDEA 199
            |...|..|.:      ||..|:          .|..:|...|...:...           .|.:|
  Fly   178 CRIPSTTLTE------DGYIFN----------LPEKTFPLPTKPAVLAM-----------PSTQA 215

  Fly   200 P------------------LLCNTT-----KKVTT---PV------VTETPLELLGCPLPLGDER 232
            |                  |..:||     :||.|   ||      .||:...|:....|..:.|
  Fly   216 PFRPQPTTAVPASRPTIEYLPPSTTQHPSYEKVQTSRRPVYLPPSPATESASSLIPKIRPRPEPR 280

  Fly   233 PILTGDGSRVLTGPITRGTV-RFSCKQGYVLEGEESSYCAKNKWSTSTIP------------KCV 284
            |..|...:.....|.....: ||...:......::..|..:::.|....|            ||.
  Fly   281 PQPTRRPTNEYLPPAAANEIPRFEPDRAPQPSNQKPIYRGEDQLSPQIFPTPQPANVPKHFAKCA 345

  Fly   285 --------KYCSTAG--------------EFDGYSTKALCTHNGQQVE-CRKPFH--PPGTEVKF 324
                    .:|:..|              .|....|..|.|.||...: ||.|.:  |....:..
  Fly   346 SALVCTSENFCNAIGVLSETPVELSPMEAAFRVPLTDCLQTENGSPGKCCRDPNYVDPWPVNLAG 410

  Fly   325 VCSTGFKTLSPLPEMRCMKGGYWNRGRQRCEQDCGQLATPIKQFSSGGYTINNTVVPWHVGLYVW 389
            ||:|..|...|                           |.:|...:     |...:||...:.
  Fly   411 VCATRNKRTKP---------------------------TGVKDLDA-----NFAEIPWQAMIL-- 441

  Fly   390 HNEKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAAKFYRNYGETTP--EEKRRD 452
             .|......|||:::....|:::|.||    ..||.:  ..||.|.::  ..|.|..  ..:...
  Fly   442 -RESSKTLICGGAIIGDQFVLSSASCV----NGLPVT--DIRVKAGEW--ELGSTNEPLPFQLTG 497

  Fly   453 VRLIEIAPGYKGRTENYYQDLALLTLDEPFELSHVIRPICVTFASFAEKESVTDDVQGKFAGWNI 517
            |:.:::.|.|...|.::  |||::.|:...|.:..|:|||::      .|...|..|...:||..
  Fly   498 VKTVDVHPDYDPSTNSH--DLAIIRLERRLEFASHIQPICIS------DEDPKDSEQCFTSGWGK 554

  Fly   518 E--NKHE----LQFVPAVSKSNSVCRRNLRDI-QADKF--CIFTQGKSLACQGDSG----GGFTS 569
            :  :.||    :.....:.::.|.|..:...: .|.||  |.|..|.:|||...|.    |.|..
  Fly   555 QALSIHEEGALMHVTDTLPQARSECSADSSSVCSATKFDSCQFDVGSALACGSGSSVRLKGIFAG 619

  Fly   570 ELPTNAFSTWNTAR 583
            |   |:.....|.|
  Fly   620 E---NSCGEGQTVR 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566	8/32 (25%)
		LDLa	70..101	CDD:197566	8/33 (24%)
		LDLa	123..157	CDD:197566	10/47 (21%)
		LDLa	167..199	CDD:238060	4/31 (13%)
		CCP	<251..284	CDD:153056	6/45 (13%)
		Sushi	309..354	CDD:278512	9/47 (19%)
		Tryp_SPc	371..616	CDD:214473	56/228 (25%)
		Tryp_SPc	371..591	CDD:304450	56/228 (25%)
scaf	NP_610180.1	FtsK	<198..>334	CDD:332908	26/146 (18%)
scaf	NP_610180.1	Tryp_SPc	428..616	CDD:238113	50/211 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435558
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030