DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and spirit

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	295	Identity:	75/295 - (25%)
Similarity:	122/295 - (41%)	Gaps:	76/295 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 EQDCGQL--ATPIKQFSS------GGYTINNTVVPWHVGLYVWHNEKD--YHFQCGGSLLTPDLV 409
            :|.|.:|  .:.:|:...      ||........|:...| .|.:..|  .:::|||:|:..:.|
  Fly   110 QQACNELNKVSKVKEIDEFFVSVVGGMPTRPREFPFMAAL-GWRSNFDQRIYYRCGGALIANNFV 173

  Fly   410 ITAAHCVYDEGTRLPYSYDTFRVIAAKFYRNYGE--TTPEEKRRDVRLIEIAPGYKGRTENYYQD 472
            :|||||. |.|...|..           .|..|:  |..|.:...:|.:.|.|.|...|.  |.|
  Fly   174 LTAAHCA-DLGGEPPSQ-----------VRLGGDNLTLTEGEDISIRRVIIHPDYSASTA--YND 224

  Fly   473 LALLTLDEPFELSHVIRPICVTFASFAEKESVTDDV-------QGKFAGWNIENKHELQFVPAVS 530
            :|||.|:...:..  ::|.|:    :.:|| ||:.:       |..|||.   :..:|..||..|
  Fly   225 IALLELETAAKPE--LKPTCI----WTQKE-VTNTLVTAIGYGQTSFAGL---SSAQLLKVPLKS 279

  Fly   531 KSNSVCRRNLRDIQADKFCIFTQ-------GKSLACQGDSGG-------------GFTS------ 569
            .||..|:.:.:..|..:..:.||       |:...|||||||             |.||
  Fly   280 VSNEECQHHYQKDQLAQGVLGTQMCAGDITGERDTCQGDSGGPLLMQDGLLGYVVGITSLGQGCA 344

  Fly   570 ELPTNAFSTWNTARHFLFGV------ISNAPNADQ 598
            ..|.:.::..::...::.|:      ::|||..:|
  Fly   345 SGPPSVYTRVSSFVDWIEGIVWPAQQVTNAPQPNQ 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512
		Tryp_SPc	371..616	CDD:214473	71/271 (26%)
		Tryp_SPc	371..591	CDD:304450	67/262 (26%)
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	66/256 (26%)
		Tryp_SPc	132..361	CDD:214473	66/253 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030