DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and Sp212

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster

Alignment Length:	258	Identity:	74/258 - (28%)
Similarity:	105/258 - (40%)	Gaps:	65/258 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 CGQ--LATPI----KQFSSGGYTINNTVVPWHVGLYVWHNE-KDYHFQCGGSLLTPDLVITAAHC 415
            ||:  ..||.    .:|..|.|       ||...:|  |.| :...|:|.|||::..:||:||||
  Fly   267 CGREGSTTPFIVRGNEFPRGQY-------PWLSAVY--HKEVRALAFKCRGSLISSSIVISAAHC 322

  Fly   416 VYDEGTRLP----------YSYDTFRVIAAKFYRNYGETTPEEKRRDVRLIEIAPGYKGRTENYY 470
            |:    |:.          |..|           :|||...|  .|:|..:...|.|  .|.:|.
  Fly   323 VH----RMTEDRVVVGLGRYDLD-----------DYGEDGAE--MRNVMRLLWHPDY--NTRSYS 368

  Fly   471 Q-DLALLTLDEPFELSHVIRPICVTFASFAEKESVTDDVQGKFAGW-NIENKHELQF---VPAVS 530
            . |:||:|::.|...:.:|.|||:    :..:.|.|....|..||| ..|:....|:   |.|..
  Fly   369 DADIALITIERPVTFNDIIAPICM----WTVEASRTVSTTGFIAGWGRDEDSSRTQYPRVVEAEI 429

  Fly   531 KSNSVCRRNLRD--IQADKFCIFTQGKSLACQGDSGGGFTSELPTNAFSTWNTARHFLFGVIS 591
            .|.:||....|.  :.....|...:..|..|.||||||    |.......|     .|.|::|
  Fly   430 ASPTVCASTWRGTMVTERSLCAGNRDGSGPCVGDSGGG----LMVKQGDRW-----LLRGIVS 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512
		Tryp_SPc	371..616	CDD:214473	69/239 (29%)
		Tryp_SPc	371..591	CDD:304450	68/237 (29%)
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	70/248 (28%)
		Tryp_SPc	277..511	CDD:214473	70/248 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468797
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930