Protein Alignment modSP and F10

DIOPT Version :9

• Sequence 1: NP_536776.2
• Gene: modSP / 42032
• FlyBaseID: FBgn0051217
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 528
• Identity: 112/528 - (21%)
• Similarity: 177/528 - (33%)
• Gaps: 172/528 - (32%)

  Fly   163 GHMECPAYSFKCGTGGCISGSLSCNGENDCYDGSDEAPLLCNTTKKVTTPVVTETPLELLGCPLP 227
            ||:|          ..|:..:.|.....:.::.||:.....|..|
Human    51 GHLE----------RECMEETCSYEEAREVFEDSDKTNEFWNKYK-------------------- 85

  Fly   228 LGDERPILTGDGSRVLTGPITRGTVRFSCKQGYVLEGEESSYCAKNKWSTSTIPKCVKYCSTAGE 292
                      ||.:..|.|...   :..||.|.   ||.:..|.:.
Human    86 ----------DGDQCETSPCQN---QGKCKDGL---GEYTCTCLEG------------------- 115

  Fly   293 FDGYS----TKALCT-HNGQQVECRKPFHPPGTEVKFVCSTGFKTLSPLPEMRCMKGGYWNRGRQ 352
            |:|.:    |:.||: .||   :|.:..|.....|...|:.|: ||:...: .|:..|.:..|:|
Human   116 FEGKNCELFTRKLCSLDNG---DCDQFCHEEQNSVVCSCARGY-TLADNGK-ACIPTGPYPCGKQ 175

  Fly   353 RCEQ------------------------DCGQLATPIKQFS-------------------SGGYT 374
            ..|:                        |...|......|.                   .||..
Human   176 TLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQE 240

  Fly   375 INNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAAKFYR 439
            ..:...||...|.   ||::..| |||::|:...::|||||:|.               |.:|..
Human   241 CKDGECPWQALLI---NEENEGF-CGGTILSEFYILTAAHCLYQ---------------AKRFKV 286

  Fly   440 NYGE--TTPEEKRRDVRLIEIAPGYKGRT-ENYYQDLALLTLDEPFELSHVIRPICVTFASFAEK 501
            ..|:  |..||....|..:|:...:...| |.|..|:|:|.|..|......:.|.|:....:||.
Human   287 RVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAES 351

  Fly   502 ESVTDDVQGKFAGWNIENKHE---------LQFVPAVSKSNSVCRRNLRDIQADKFCI-FTQGKS 556
            ..:|... |..:|:.  ..||         :..||.|.: ||....:...|..:.||. :...:.
Human   352 TLMTQKT-GIVSGFG--RTHEKGRQSTRLKMLEVPYVDR-NSCKLSSSFIITQNMFCAGYDTKQE 412

  Fly   557 LACQGDSGGGFTSELPTNAFSTWNTARHFLFGVISNAPNADQCAH--SLTVMTNIQHFEDMILNA 619
            .||||||||...:.....         :|:.|::|   ..:.||.  ...:.|.:..|    |..
Human   413 DACQGDSGGPHVTRFKDT---------YFVTGIVS---WGEGCARKGKYGIYTKVTAF----LKW 461

  Fly   620 MNRSVETR 627
            ::||::||
Human   462 IDRSMKTR 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060	4/31 (13%)
		CCP	<251..284	CDD:153056	6/32 (19%)
		Sushi	309..354	CDD:278512	11/44 (25%)
		Tryp_SPc	371..616	CDD:214473	66/259 (25%)
		Tryp_SPc	371..591	CDD:304450	61/232 (26%)
F10	NP_000495.1	GLA	25..85	CDD:214503	8/43 (19%)
		EGF_CA	86..122	CDD:238011	12/60 (20%)
		FXa_inhibition	129..164	CDD:317114	10/39 (26%)
		O-glycosylated at one site	183..203		0/19 (0%)
		Tryp_SPc	235..464	CDD:238113	67/267 (25%)
		O-glycosylated at one site	476..485

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910