DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment modSP and try-4

DIOPT Version :9

Sequence 1:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_508030.4	Gene:	try-4 / 185148	WormBaseID:	WBGene00006622	Length:	324	Species:	Caenorhabditis elegans

Alignment Length:	321	Identity:	79/321 - (24%)
Similarity:	117/321 - (36%)	Gaps:	105/321 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   356 QDCG-QLATPIKQFSSGGYTINNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDLVITAAH----- 414
            :.|| |..:.||.|            ||.|...|     |...:.|||:::|..:|||||
Worm    45 ESCGIQQESKIKNF------------PWAVSFTV-----DGVNRLGGSIISPYHIITAAHGFITT 92

  Fly   415 -------CVYDEGTRLPYSYDTFRVIAAKFYRN-----YGET-----------TPEEKRRD---- 452
                   | .::..:.|.| ..:|.|  ||.|:     ||.|           .|..|:.|
Worm    93 IGSRGNLC-ENKNWKKPNS-SIYRSI--KFLRDTRKVAYGGTCIRGHTDKYPNDPRCKKSDVIHN 153

  Fly   453 -VRLI----EIAPG--YKGRTENYYQDLALLTLDEPFELSHVIRPICVTFASFAEKESVTDDVQG 510
             ||.:    |.|..  .||      .|.|::.:::....|..:||||:...:....:|:.
Worm   154 KVRAVLVDGEFASSNCLKG------HDWAIVEVEKRIHFSENVRPICLPRPNMYYTKSLA----- 207

  Fly   511 KFAGWN---IENK-----HELQFVPAVSKSNSVCRRNLRD---IQADKF-CIFTQGKS-----LA 558
             ..||.   |.|:     ||:..     :.:..|:|...|   ..||.| |..:...|     ..
Worm   208 -VPGWGRSYIFNESGPLIHEIPM-----RIDRDCKRPWSDRLPADADDFICATSMNVSNYSAPRT 266

  Fly   559 CQGDSGGGFTSELPTNAFSTWNTARHFLFGVISNAPNADQC-AHSLTVMTNIQHFEDMILN 618
            |.||||||.       .:...|..|.||..:.|.....  | ::.|...|.:..:.::|.|
Worm   267 CHGDSGGGL-------EYRDDNYGRAFLIAITSFGTRG--CPSNMLARFTRVDMYLNLICN 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512
		Tryp_SPc	371..616	CDD:214473	71/301 (24%)
		Tryp_SPc	371..591	CDD:304450	67/275 (24%)
try-4	NP_508030.4	Tryp_SPc	51..318	CDD:238113	75/313 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100