DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14906 and Mettl4

DIOPT Version :9

Sequence 1:	NP_650573.1	Gene:	CG14906 / 42030	FlyBaseID:	FBgn0015351	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	XP_038939714.1	Gene:	Mettl4 / 316731	RGDID:	1306451	Length:	474	Species:	Rattus norvegicus

Alignment Length:	288	Identity:	95/288 - (32%)
Similarity:	141/288 - (48%)	Gaps:	47/288 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 SLEDLHLVNEYLELLSKPVEPEDSSPMKRHWEDGYNVPQLHGANESGRMQRFLRVDGSRGVYLIP 131
            ||.|:.|  :.|:|:...|...:.....|..|:          |.|  ..:.:.:.|.|  ||:|
  Rat   212 SLNDMEL--QTLQLMGDDVFVTELDLSSRIIEN----------NSS--FSKMITLMGQR--YLLP 260

  Fly   132 NQSRFFNHNVDNLPALLHQLLPAYDLIVLDPPWRNKYIRRLKRAKPELGYSMLSNEQLSHIPLSK 196
            .:|.|...::..:..||: ....:|:||:||||.||.::|..|      |:.||.:|:..:|:.|
  Rat   261 PKSSFLLSDISCMQPLLN-CSKTFDVIVIDPPWENKSVKRSNR------YNSLSPQQIKRMPVPK 318

  Fly   197 LTHPRSLVAIWCTNSTLHQLALEQQLLPSWNLRLLHKLRWYKLSTDHELIAPPQSDLTQKQPYEM 261
            |..|..||..|.||...|...::::|.|||::.::.:..|.|::...|.:.|  .|...|:|||.
  Rat   319 LAAPDCLVVTWVTNRQKHLCFVKEELYPSWSVEVIAEWYWVKITNSGEFVFP--LDSLHKKPYEC 381

  Fly   262 LY---------VACRSDASENYGKDIQQTELIFSVPSIVHSHKPPLLSWLREHLLLDKDQLEP-- 315
            |.         :|.|::|...  ..:....||.|||..:|||||||...|       ||.::|
  Rat   382 LVLGRVKEKTALALRNEAVRT--PPVPDQRLIVSVPCALHSHKPPLAEVL-------KDYIKPGG 437

  Fly   316 NCLELFARYLHPHFTSIGLEVLKL--MD 341
            .|||||||.|.|.:.|.|.||||.  ||
  Rat   438 QCLELFARNLQPGWMSWGNEVLKFQHMD 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14906	NP_650573.1	MT-A70	155..335	CDD:282866	69/190 (36%)
Mettl4	XP_038939714.1	MT-A70	283..457	CDD:382774	69/190 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337082
Domainoid	1	1.000	114	1.000	Domainoid score	I5954
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H35305
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1496188at2759
OrthoFinder	1	1.000	-	-		FOG0004635
OrthoInspector	1	1.000	-	-		oto97905
orthoMCL	1	0.900	-	-		OOG6_105628
Panther	1	1.100	-	-	LDO	PTHR12829
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3250
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.850