DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT3 and CCT7

DIOPT Version :9

Sequence 1:	NP_001189236.1	Gene:	CCT3 / 42029	FlyBaseID:	FBgn0015019	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_012424.1	Gene:	CCT7 / 853333	SGDID:	S000003647	Length:	550	Species:	Saccharomyces cerevisiae

Alignment Length:	555	Identity:	177/555 - (31%)
Similarity:	292/555 - (52%)	Gaps:	37/555 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 FGGQQP-ILVLSQNTKRESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGN 65
            ||.|.| |:||.:.|....|:...:.||.|..|:.:.::..|||.....:::.......::|||.
Yeast     3 FGSQTPTIVVLKEGTDASQGKGQIISNINACVAVQEALKPTLGPLGSDILIVTSNQKTTISNDGA 67

  Fly    66 AILREITVQHPAAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREA 130
            .||:.:.|.|||||::::|:|.||.|||||||||.:||||::..|:|||::.|...:|::.||:|
Yeast    68 TILKLLDVVHPAAKTLVDISRAQDAEVGDGTTSVTILAGELMKEAKPFLEEGISSHLIMKGYRKA 132

  Fly   131 LEDIVGHLQSQLSIQLDVKDKAKMADVVKACVGT----KFIGKWSDLAVKIALDAVETVTLSENG 191
            :...|..: ::|::.: ..:|:...::::.|..|    |.|...:|..||:.:|||  ::|..|
Yeast   133 VSLAVEKI-NELAVDI-TSEKSSGRELLERCARTAMSSKLIHNNADFFVKMCVDAV--LSLDRN- 192

  Fly   192 RLEVDIKRYAKVEKIPGGAIEESCVLKGVMINKDVTH------PKMRRLIENPRIVLLDCSLEYK 250
              ::|.|... ::||||||:|||..:.||...|..::      ||.   ..||:|:.|:..||.|
Yeast   193 --DLDDKLIG-IKKIPGGAMEESLFINGVAFKKTFSYAGFEQQPKK---FNNPKILSLNVELELK 251

  Fly   251 KGESQTNVEIIGEQDFTRMLQIEEEFVQRICADIIAVKPDLVFTEKGVSDLAQHYLLKAGITAIR 315
            ..:....|.:...:|:..::..|.:.:......:.....::|.::..:.|||..:.....|....
Yeast   252 AEKDNAEVRVEHVEDYQAIVDAEWQLIFEKLRQVEETGANIVLSKLPIGDLATQFFADRNIFCAG 316

  Fly   316 RLRKTDNLRIARACGATIVNRTEELTEKDVGTGAGLFEVKKIGDEYFTFVTECKEPKACTILLRG 380
            |:...|..|:.:|.|.:|.:.|.::..:.:||.| |||..:||.|.:.....|.:.|.||:||||
Yeast   317 RVSADDMNRVIQAVGGSIQSTTSDIKPEHLGTCA-LFEEMQIGSERYNLFQGCPQAKTCTLLLRG 380

  Fly   381 ASKDILNETERNLQDALHVARNLVLEPRLVAGGGAVEMAASQLLT--RKQVKGP----YTAVAHA 439
            .::.::.|.||:|.||:.:.:..:....:||||||.||..|:.|.  .|.:.|.    ..|.|.|
Yeast   381 GAEQVIAEVERSLHDAIMIVKRALQNKLIVAGGGATEMEVSKCLRDYSKTIAGKQQMIINAFAKA 445

  Fly   440 LEIIPRTLAQNCGANTIRALTALRAKHASHTGDGVCAWGIDGESGEIVDMNVKNIWEPLAVKLQT 504
            ||:|||.|.:|.|.:.|..|..||..|:.    |...:|:..|:..|.|...|.:|||..||:..
Yeast   446 LEVIPRQLCENAGFDAIEILNKLRLAHSK----GEKWYGVVFETENIGDNFAKFVWEPALVKINA 506

  Fly   505 YKTAVETAILLLRIDDIVSGSKKRGGNEPTNPAAM 539
            ..:|.|...|:|.:|:.::..    |:|..|...|
Yeast   507 LNSATEATNLILSVDETITNK----GSESANAGMM 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_001189236.1	chap_CCT_gamma	7..528	CDD:274085	170/537 (32%)
CCT3	NP_001189236.1	TCP1_gamma	7..524	CDD:239453	170/533 (32%)
CCT7	NP_012424.1	TCP1_eta	9..529	CDD:239456	169/539 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810