Protein Alignment CCT3 and CCT4

DIOPT Version :10

• Sequence 1: NP_650572.2
• Gene: CCT3 / 42029
• FlyBaseID: FBgn0015019
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_010138.1
• Gene: CCT4 / 851412
• SGDID: S000002302
• Length: 528
• Species: Saccharomyces cerevisiae
• Alignment Length: 534
• Identity: 161/534 - (30%)
• Similarity: 289/534 - (54%)
• Gaps: 52/534 - (9%)

  Fly    17 RESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGNAILREITVQHPAAKSM 81
            :|..::|:..||.|.:::||.|||.|||:.|.||:....|.|:::|||:.||:::.:.||.|:.:
Yeast    14 KEKPQEVRKANIIAARSVADAIRTSLGPKGMDKMIKTSRGEIIISNDGHTILKQMAILHPVARML 78

  Fly    82 IEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREALEDIVGHLQSQLSIQL 146
            :|::..||.|.|||||||::|.|.:|.|||..|.:.||||:|..:::.|.:..|..| .::..::
Yeast    79 VEVSAAQDSEAGDGTTSVVILTGALLGAAERLLNKGIHPTIIADSFQSAAKRSVDIL-LEMCHKV 142

  Fly   147 DVKDKAKMADVVKACVGTKFIGKWSDLAVKIALDAVETVTLSENGRLEVDIKRYAKVEKIPGGAI 211
            .:.|:.::.......:.:|.:.::|.....:|:|:|  :.:|:.....||:.....|:|: ||.|
Yeast   143 SLSDREQLVRAASTSLSSKIVSQYSSFLAPLAVDSV--LKISDENSKNVDLNDIRLVKKV-GGTI 204

  Fly   212 EESCVLKGVMIN----KDVTHPKMRRLIENPRIVLLDCSLEYKKGESQTNVEIIGEQDFTRMLQI 272
            :::.::.||::.    |....|..:   |..:|.|:...:...|.:::.|:.:...:...::|:.
Yeast   205 DDTEMIDGVVLTQTAIKSAGGPTRK---EKAKIGLIQFQISPPKPDTENNIIVNDYRQMDKILKE 266

  Fly   273 EEEFVQRICADIIAVKPDLVFTEK-----GVSDLAQHYLLKAGITAIRRLRKTDNLRIARACGAT 332
            |..::..||..|...|.:::..:|     .|:|||.|:|.|..|..::.:.:.:...:::..|..
Yeast   267 ERAYLLNICKKIKKAKCNVLLIQKSILRDAVNDLALHFLSKLNIMVVKDIEREEIEFLSKGLGCK 331

  Fly   333 IVNRTEELTEKDVGTGAGLFEVKKIGDEYFTFVTECKEPKA---CTILLRGASKDILNETERNLQ 394
            .:...|..||..:|:...:.|:...|.: ...||..:...|   .::::|||:..|::||||:|.
Yeast   332 PIADIELFTEDRLGSADLVEEIDSDGSK-IVRVTGIRNNNARPTVSVVIRGANNMIIDETERSLH 395

  Fly   395 DALHVARNLVLEPRLVAGGGAVEMAASQLLTR--KQVKGPYTAV----AHALEIIPRTLAQNCGA 453
            |||.|.|.||.|..|:|||||.|:..|:.|::  :.::|....:    |.|||:||.|||:|.|.
Yeast   396 DALCVIRCLVKERGLIAGGGAPEIEISRRLSKEARSMEGVQAFIWQEFASALEVIPTTLAENAGL 460

  Fly   454 NTIRALTALRAKHASHTGDGVCAWGIDGESGEIVD-MNVK----------NIWEPLAVKLQTYKT 507
            |:|:.:|.||:||               |:||:.| ::|:          :|.:|:.|.......
Yeast   461 NSIKVVTELRSKH---------------ENGELNDGISVRRSGTTNTYEEHILQPVLVSTSAITL 510

  Fly   508 AVETAILLLRIDDI 521
            |.|....:||||||
Yeast   511 ASECVKSILRIDDI 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_650572.2	chap_CCT_gamma	7..528	CDD:274085	161/534 (30%)
CCT4	NP_010138.1	chap_CCT_delta	11..528	CDD:274083	161/534 (30%)