Protein Alignment CCT3 and MKKS

DIOPT Version :9

• Sequence 1: NP_001189236.1
• Gene: CCT3 / 42029
• FlyBaseID: FBgn0015019
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_061336.1
• Gene: MKKS / 8195
• HGNCID: 7108
• Length: 570
• Species: Homo sapiens
• Alignment Length: 559
• Identity: 116/559 - (20%)
• Similarity: 214/559 - (38%)
• Gaps: 97/559 - (17%)

  Fly    37 VIRTCLGPQAMLKMLMDPMGGIV-MTNDGNAILREITVQHPAAKSMIEIARTQDEEVGDGTTSVI 100
            ::.:|.||...||.|.:..||.| .|:..:|:|..:.|.||..|.:....:.......|......
Human    32 IVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDCGLFTA 96

  Fly   101 VLAGEMLAAAEPFLQQQIHPTVIIRAYREALEDIVGHLQSQ---LSIQLDVKDKAKMADVVK--- 159
            :|...::   |...:..:.||.:||..:..|...:.:|:|:   ..|.:|......:..:|:
Human    97 ILCCNLI---ENVQRLGLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSIL 158

  Fly   160 ----ACVGTKFIGKWSDLAVKIALDAVETVTLSENGRLEVDIKRYAKVEKIPGGAIEESCVLKGV 220
                ||:.|:   |.::....:.|.|. .:|:.||....:.:.: :.:..:.|..:.:|.||.|:
Human   159 TSKPACMLTR---KETEHVSALILRAF-LLTIPENAEGHIILGK-SLIVPLKGQRVIDSTVLPGI 218

  Fly   221 MINKDVTHPKMRRLIENPRIVLLDCSLEYKKGESQTNVEIIGEQDFTRMLQIEEEFVQRIC---A 282
            :|  :::..::.||:...:...|..:|........|:....|....:..:.:|...:.::.   .
Human   219 LI--EMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQLLNLGR 281

  Fly   283 DIIAVKPDLVFTEKGVSD-----LAQHYLL---KAGITAIRRLRKTDNLRIARACGATIVNRTEE 339
            .:|:...|||..:|.:..     |..|.::   :.|:|.:..|.|....:...:.|:...|....
Human   282 QLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGS 346

  Fly   340 LTEKDVGTGAGLFEVKKIGDEYFTFVTECKEPKACTILLRGASKDILNETERNLQDALHVARNLV 404
            :  |||.|.       |.|.::| |.....|...|::||...:....:|.:...|.||||.:..:
Human   347 V--KDVCTA-------KFGSKHF-FHLIPNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTL 401

  Fly   405 LEPRLVAGGGAVEMAASQLLTRKQVKGPYT-----------------AVAHALEIIPRTLAQNCG 452
            .||..:.|||..|...:..:..|....|.:                 |...|||.:..:|..:.|
Human   402 KEPWALLGGGCTETHLAAYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGG 466

  Fly   453 ANTIRALTALRAKHA-SHTGDGVCA--W---------GIDGESGEIVDMNVKNIWEP-------- 497
                ..||.::..|. |...|..|.  |         |:.....|:....:::...|
Human   467 ----EILTDMKYGHLWSVQADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLP 527

  Fly   498 --------------LAVKLQTYKTAVETAILLLRIDDIV 522
                          |..||...:.|||||.|:|.:..::
Human   528 HEAVGSASNLTLDCLTAKLSGLQVAVETANLILDLSYVI 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_001189236.1	chap_CCT_gamma	7..528	CDD:274085	116/559 (21%)
		TCP1_gamma	7..524	CDD:239453	116/559 (21%)
MKKS	NP_061336.1	Cpn60_TCP1	29..569	CDD:278544	116/559 (21%)
		chaperonin_like	32..476	CDD:295468	98/467 (21%)
		Substrate-binding apical domain	198..370		35/184 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810