Protein Alignment CCT3 and TCP1

DIOPT Version :9

• Sequence 1: NP_001189236.1
• Gene: CCT3 / 42029
• FlyBaseID: FBgn0015019
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_110379.2
• Gene: TCP1 / 6950
• HGNCID: 11655
• Length: 556
• Species: Homo sapiens
• Alignment Length: 545
• Identity: 173/545 - (31%)
• Similarity: 286/545 - (52%)
• Gaps: 38/545 - (6%)

  Fly    17 RESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGNAILREITVQHPAAKSM 81
            |.:|..::.:|:.|..:||:::::.|||..:.|||:|.:|.:.:||||..||:.:.|:|||||.:
Human    11 RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVL 75

  Fly    82 IEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREALEDIVGHLQSQLSIQL 146
            .|:|..||:|||||||||:::|.|:|..|:..::|:||||.:|..||.|.::.|.::...|.:..
Human    76 CELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140

  Fly   147 DVKDKAKMADVVKACVGTKFIGKWSDLAVKIALDAVETVTLSENGRLEVDIK---RY----AKVE 204
            |...:..:.:..|..:.:|.||...|....:.:|||..:..:       ||:   ||    ..:.
Human   141 DELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYT-------DIRGQPRYPVNSVNIL 198

  Fly   205 KIPGGAIEESCVLKGVMINKDVTHPKMRRLIENPRIVLLDCSLEYKKGESQTNVEIIGEQDFTRM 269
            |..|.:..||.::.|..:|..|....|.:.|.|.:|..||.||:..|.:....|.|...:...::
Human   199 KAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQI 263

  Fly   270 LQIEEEFVQRICADIIAVKPDLVFTEKGVSDLAQHYLLKAGITAIRRLRKTDNLRIARACGATIV 334
            .|.|.:..:.....|:|...:::.|..|:.|:...|.::||..|:||:.|.|..|||:|.||||:
Human   264 RQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATIL 328

  Fly   335 NRTEELTEKDVGTGAGLFEV-----KKIGDEYFTFVTECKEPKACTILLRGASKDILNETERNLQ 394
            :....|..::....|.|.:.     ::|.|:....:...|...:.:|:||||:..:.:|.||:|.
Human   329 STLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLH 393

  Fly   395 DALHVARNLVLEPRLVAGGGAVEMA--------ASQLLTRKQVKGPYTAVAHALEIIPRTLAQNC 451
            |||.|.:.::....:|.||||||.|        |:.:.:|:|:  .....|.:|.:||.|||.|.
Human   394 DALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQL--AIAEFARSLLVIPNTLAVNA 456

  Fly   452 GANTIRALTALRAKHAS---HTGDGVCAW-GIDGESGEIVDMNVKNIWEPLAVKLQTYKTAVETA 512
            ..::...:..|||.|..   :.......| |:|..:|:..|.....::||..||:::.|.|.|.|
Human   457 AQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAA 521

  Fly   513 ILLLRIDDIV-----SGSKKRGGNE 532
            |.:|||||::     |...|.|..|
Human   522 ITILRIDDLIKLHPESKDDKHGSYE 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_001189236.1	chap_CCT_gamma	7..528	CDD:274085	170/539 (32%)
		TCP1_gamma	7..524	CDD:239453	169/535 (32%)
TCP1	NP_110379.2	TCP1_alpha	9..535	CDD:239451	169/532 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810