DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT3 and CCT7

DIOPT Version :9

Sequence 1:	NP_001189236.1	Gene:	CCT3 / 42029	FlyBaseID:	FBgn0015019	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster

Alignment Length:	559	Identity:	172/559 - (30%)
Similarity:	291/559 - (52%)	Gaps:	42/559 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QQPILVLSQNTKRESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGNAILR 69
            |..|::|.:.|....|:...:.||.|.::|.|.:||.|||:.|.|:::|..|...::|||..|::
  Fly     2 QPQIVLLKEGTDSSQGKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIMK 66

  Fly    70 EITVQHPAAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREALEDI 134
            .:.:.|||||::::||::||.|||||||||::||||.|...:||:::.:||.|||:|.|:||:..
  Fly    67 LLEIIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLC 131

  Fly   135 VGHLQSQLSIQLDVKDKAKMADVVKACVGT----KFIGKWSDLAVKIALDAV----ETVTLSENG 191
            :..: :::::|:..:.|.:...:::.|..|    |.|.:..|...:|.:|||    |.:.|:..|
  Fly   132 MEKI-NEMAVQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDELLPLNMIG 195

  Fly   192 RLEVDIKRYAKVEKIPGGAIEESCVLKGVMINKDVTH------PKMRRLIENPRIVLLDCSLEYK 250
                       ::|:.||::|||.::.||...|..::      ||.   .:|.:|.||:..||.|
  Fly   196 -----------IKKVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKS---YDNCKIALLNIELELK 246

  Fly   251 KGESQTNVEIIGEQDFTRMLQIEEEFVQRICADIIAVKPDLVFTEKGVSDLAQHYLLKAGITAIR 315
            .......:.:...:::.:::..|.:.:....|.|.....::|.::..:.|:|..|.....|....
  Fly   247 AERDNAEIRVDNVKEYQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAG 311

  Fly   316 RLRKTDNLRIARACGATIVNRTEELTEKDVGTGAGLFEVKKIGDEYFTFVTECKEPKACTILLRG 380
            |:.:.|..|..:|||..::....::....:|. ...||.:::|.|.|.....|...|..|::|||
  Fly   312 RVPEEDLKRTMKACGGAVMTTANDIKPNVLGL-CEHFEERQVGGERFNLFQGCPNAKTSTLILRG 375

  Fly   381 ASKDILNETERNLQDALHVARNLVLEPRLVAGGGAVEMAASQLLT--RKQVKGP----YTAVAHA 439
            .::..|.||||:|.||:.:.|..:....:||||||:||..|:||.  .:.:.|.    ..|:|..
  Fly   376 GAEQFLEETERSLHDAIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKG 440

  Fly   440 LEIIPRTLAQNCGANTIRALTALRAKHASHTGDGVCAWGIDGESGEIVDMNVKNIWEPLAVKLQT 504
            ||||||.|..|.|.:....|..||.|||    .|...:|:|....:|.|...:.:|||..:|:..
  Fly   441 LEIIPRQLCDNAGFDATNILNKLRQKHA----QGGQWYGVDINKEDISDNYEQCVWEPSIIKINA 501

  Fly   505 YKTAVETAILLLRIDDIVSGSKKRGGNEPTNPAAMAQGQ 543
            ...|.|.|.::|.:|:.:...|  .|..|.....|..|:
  Fly   502 LTAAAEAACMILSVDETIKSPK--AGEPPMAGGGMGMGR 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_001189236.1	chap_CCT_gamma	7..528	CDD:274085	167/540 (31%)
CCT3	NP_001189236.1	TCP1_gamma	7..524	CDD:239453	166/536 (31%)
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	168/543 (31%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	167/541 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453460
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D38420at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850