DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT3 and cct7

DIOPT Version :9

Sequence 1:	NP_001189236.1	Gene:	CCT3 / 42029	FlyBaseID:	FBgn0015019	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_001032347.1	Gene:	cct7 / 407957	XenbaseID:	XB-GENE-988120	Length:	542	Species:	Xenopus tropicalis

Alignment Length:	554	Identity:	178/554 - (32%)
Similarity:	289/554 - (52%)	Gaps:	46/554 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PILVLSQNTKRESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGNAILREI 71
            |:::|.:.|....|....:.||.|.:.||:.:||.|||:.|.|:::|..|...::|||..||:.:
Frog     5 PVILLKEGTDTSQGVPQLVSNINACQVIAEAVRTTLGPRGMDKLIVDDRGKATISNDGATILKLL 69

  Fly    72 TVQHPAAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREALEDIVG 136
            .|.|||||::::||::||.|||||||||.:||.|.:...:|::::.:||.:||||||.|.:..||
Frog    70 DVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFMKQVKPYVEEGLHPQIIIRAYRTATQLAVG 134

  Fly   137 HLQSQLSIQLDVKDKAKMADVVKACVGT----KFIGKWSDLAVKIALDAVETVTLSENGRLEVDI 197
            .:: ::::.:..:||.:...:::.|..|    |.|....|...|:.:|||..:    :..|::
Frog   135 KIR-EIAVTVKKEDKEEQRLLLEKCAATALSSKLIALQKDFFAKMVVDAVSLL----DDLLQL-- 192

  Fly   198 KRYAKVEKIPGGAIEESCVLKGVMINKDVTH------PKMRRLIENPRIVLLDCSLEYKKGESQT 256
             :...::|:.|||:|:|.::.||...|..::      ||.   .|:|:|.||:..||.|..:...
Frog   193 -KMIGIKKVQGGALEDSHLVAGVAFKKTFSYAGFEMQPKK---YESPKISLLNVELELKAEKDNA 253

  Fly   257 NVEIIGEQDFTRMLQIEEEFVQRICADIIAVKPDLVFTEKGVSDLAQHYLLKAGITAIRRLRKTD 321
            .|.:...:|:..::..|...:......|......:|.::..:.|:|..|.....:....|:.:.|
Frog   254 EVRVSNIEDYQAIVDAEWNILYDKLEKIYKSGAKVVLSKLPIGDVATQYFADRDLFCAGRVPEED 318

  Fly   322 NLRIARACGATIVNRTEELTEKDVGTGAGLFEVKKIGDEYFTFVTECKEPKACTILLRGASKDIL 386
            ..|...|||.:|......||: ||.....|||..::|.|.:.|.|.|.:.|.|||:|||.::..:
Frog   319 LKRTMMACGGSIQTSVNALTD-DVLGHCALFEEAQVGGERYNFFTGCPKAKTCTIILRGGAEQFM 382

  Fly   387 NETERNLQDALHVARNLVLEPRLVAGGGAVEMAASQLL---------TRKQVKGPYTAVAHALEI 442
            .||||:|.||:.:.|..:....:||||||:||..|:.|         .::.:.|.|   |.||||
Frog   383 EETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGSY---AKALEI 444

  Fly   443 IPRTLAQNCGANTIRALTALRAKHASHTGDGVCAWGIDGESGEIVDMNVKNIWEPLAVKLQTYKT 507
            |||.|..|.|.:....|..||||||    .|...:|:|..:.:|.|.....:|||..|::.....
Frog   445 IPRQLCDNAGFDATNILNKLRAKHA----QGGMWYGVDVNNEDIADNFDACVWEPAIVRINALTA 505

  Fly   508 AVETAILLLRIDDIVSGSKK--------RGGNEP 533
            |.|.|.|:|.:|:.:...:.        ||...|
Frog   506 ASEAACLVLSVDETIKNPRSSMDGAPAGRGRGRP 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_001189236.1	chap_CCT_gamma	7..528	CDD:274085	175/547 (32%)
CCT3	NP_001189236.1	TCP1_gamma	7..524	CDD:239453	175/535 (33%)
cct7	NP_001032347.1	TCP1_eta	5..525	CDD:239456	175/538 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000