DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT3 and cct3

DIOPT Version :9

Sequence 1:	NP_001189236.1	Gene:	CCT3 / 42029	FlyBaseID:	FBgn0015019	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_989339.1	Gene:	cct3 / 394965	XenbaseID:	XB-GENE-6250478	Length:	548	Species:	Xenopus tropicalis

Alignment Length:	549	Identity:	385/549 - (70%)
Similarity:	457/549 - (83%)	Gaps:	15/549 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFGGQQPILVLSQNTKRESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGN 65
            |.|  :|:||||||.|||||||||..||.|.|.|||:|||||||:||:|||:|||||||||||||
Frog     1 MMG--RPVLVLSQNIKRESGRKVQSGNINAAKTIADIIRTCLGPRAMMKMLLDPMGGIVMTNDGN 63

  Fly    66 AILREITVQHPAAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREA 130
            ||||||.||||||||||||:|||||||||||||||:||||||:.||.||:||:||||:|.|||:|
Frog    64 AILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEQFLEQQMHPTVVISAYRKA 128

  Fly   131 LEDIVGHLQSQLSIQLDVKDKAKMADVVKACVGTKFIGKWSDLAVKIALDAVETVTLSENGRLEV 195
            |:|:|..|: ::|..:|..|:..|..::.:.|.||.|.:|:|:|..||||||:||.|.||||.|:
Frog   129 LDDMVSTLK-EISTPVDTNDRELMLKIINSAVNTKAIKRWADMACGIALDAVKTVELEENGRKEI 192

  Fly   196 DIKRYAKVEKIPGGAIEESCVLKGVMINKDVTHPKMRRLIENPRIVLLDCSLEYKKGESQTNVEI 260
            |||:||||||||||.||:||||:|||:|||||||||||||:||||||||||||||||||||.:||
Frog   193 DIKKYAKVEKIPGGIIEDSCVLRGVMVNKDVTHPKMRRLIKNPRIVLLDCSLEYKKGESQTEIEI 257

  Fly   261 IGEQDFTRMLQIEEEFVQRICADIIAVKPDLVFTEKGVSDLAQHYLLKAGITAIRRLRKTDNLRI 325
            ..|:||.|:||:|||::|::|.|||.:|||:|.||||:||||||||:||.||||||:|||||.||
Frog   258 TREEDFARILQMEEEYIQQVCEDIIRLKPDVVITEKGISDLAQHYLVKANITAIRRVRKTDNNRI 322

  Fly   326 ARACGATIVNRTEELTEKDVGTGAGLFEVKKIGDEYFTFVTECKEPKACTILLRGASKDILNETE 390
            ||||||.|.:||:||.|:||||||||||:||||||||||:||||:||||||:||||||:||.|.|
Frog   323 ARACGARIGSRTDELREEDVGTGAGLFEIKKIGDEYFTFITECKDPKACTIVLRGASKEILAEVE 387

  Fly   391 RNLQDALHVARNLVLEPRLVAGGGAVEMAASQLLTRKQ------VKGPYTAVAHALEIIPRTLAQ 449
            ||||||:.|.||:|::|.||.||||.||:.:.:||.|.      .:.||.|||.|||:|||||.|
Frog   388 RNLQDAMQVCRNVVIDPHLVPGGGAAEMSVAHILTEKSKTMTGVEQWPYRAVAQALEVIPRTLVQ 452

  Fly   450 NCGANTIRALTALRAKHASHTGDGVCAWGIDGESGEIVDMNVKNIWEPLAVKLQTYKTAVETAIL 514
            ||||:|||.||:||||   ||.:|...||:|||:|.:|||....|||||||||||||||||||||
Frog   453 NCGASTIRVLTSLRAK---HTQEGCQTWGVDGEAGVLVDMKELGIWEPLAVKLQTYKTAVETAIL 514

  Fly   515 LLRIDDIVSGSKKRG---GNEPTNPAAMA 540
            ||||||||||.|::|   |.:|..|...|
Frog   515 LLRIDDIVSGHKRKGEDHGRQPAAPGPQA 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_001189236.1	chap_CCT_gamma	7..528	CDD:274085	378/526 (72%)
CCT3	NP_001189236.1	TCP1_gamma	7..524	CDD:239453	375/522 (72%)
cct3	NP_989339.1	chap_CCT_gamma	5..528	CDD:274085	378/526 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	713	1.000	Domainoid score	I119
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4373
Inparanoid	1	1.050	753	1.000	Inparanoid score	I559
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D207515at33208
OrthoFinder	1	1.000	-	-		FOG0004601
OrthoInspector	1	1.000	-	-		oto103697
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1488
SonicParanoid	1	1.000	-	-		X3218
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090