Protein Alignment CCT3 and HSPD1

DIOPT Version :9

• Sequence 1: NP_001189236.1
• Gene: CCT3 / 42029
• FlyBaseID: FBgn0015019
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_002147.2
• Gene: HSPD1 / 3329
• HGNCID: 5261
• Length: 573
• Species: Homo sapiens
• Alignment Length: 616
• Identity: 145/616 - (23%)
• Similarity: 237/616 - (38%)
• Gaps: 134/616 - (21%)

  Fly     1 MFGGQQPI-LVLSQNTKRESGRKVQLE------NIQAGKAIADVIRTCLGPQAMLKMLMDPMGGI 58
            :|...:|: .||:.:..|...:.|:..      .:|....:||.:...:||:....::....|..
Human     7 VFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSP 71

  Fly    59 VMTNDGNAILREITV----QHPAAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPF--LQQQ 117
            .:|.||..:.:.|.:    ::..||.:.::|...:||.|||||:..|||..:  |.|.|  :.:.
Human    72 KVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSI--AKEGFEKISKG 134

  Fly   118 IHPTVIIRAYREALEDIVGHLQSQLSIQLDVKDKAKMADVVKACVGTKFIGK-WSDLAVKIALDA 181
            .:|..|.|....|::.::..|:.|.......::.|::|.:  :..|.|.||. .||...|:....
Human   135 ANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATI--SANGDKEIGNIISDAMKKVGRKG 197

  Fly   182 VETV----TLSENGRLEV---------------------------------DIKRYAKVEKI-PG 208
            |.||    ||  |..||:                                 ..|:.:.::.| |.
Human   198 VITVKDGKTL--NDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPA 260

  Fly   209 GAIEESCVLKGVMINKDVTHPKMRRLIENPRIVLLDCSLEYKKGESQTNVEIIGEQDFTRMLQIE 273
            ..|..:.....|:|.:||....:..|:.|          ..|.|.....|:..|..| .|..|::
Human   261 LEIANAHRKPLVIIAEDVDGEALSTLVLN----------RLKVGLQVVAVKAPGFGD-NRKNQLK 314

  Fly   274 EEFVQRICADIIAVKPDLVFTEKGVS----DLAQHYLLKAGITAIRRLRKTDNLRIARACG--AT 332
                     |:.......||.|:|::    |:..|.|.|.|...:.:    |:..:.:..|  |.
Human   315 ---------DMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTK----DDAMLLKGKGDKAQ 366

  Fly   333 IVNRTEELTEK-DVGTGAGLFEVKKIGDEYFTFVTECKEPKACTILLRGASKDI-LNETERNLQD 395
            |..|.:|:.|: ||.|..  :|.:|:.:..      .|......:|..|.:.|: :||.:..:.|
Human   367 IEKRIQEIIEQLDVTTSE--YEKEKLNERL------AKLSDGVAVLKVGGTSDVEVNEKKDRVTD 423

  Fly   396 ALHVARNLVLEPRLVAGGGAVEMAASQLL------TRKQVKGPYTAVAHALEIIPRTLAQNCGAN 454
            ||:..|..| |..:|.|||...:.....|      ...|..|        :|||.|||
Human   424 ALNATRAAV-EEGIVLGGGCALLRCIPALDSLTPANEDQKIG--------IEIIKRTL------- 472

  Fly   455 TIRALTALRAKHASHTGDGV--------CAWGIDGESGEIVDMNVKNIWEPLAVKLQTYKTAVET 511
            .|.|:|.  ||:|...|..:        ...|.|..:|:.|:|..|.|.:|..|.......|...
Human   473 KIPAMTI--AKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGV 535

  Fly   512 AILLLRIDDIVSGSKKRGGNEPTNPAAMAQG 542
            |.||...:.:|:...|    |..:|...|.|
Human   536 ASLLTTAEVVVTEIPK----EEKDPGMGAMG 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_001189236.1	chap_CCT_gamma	7..528	CDD:274085	139/594 (23%)
		TCP1_gamma	7..524	CDD:239453	139/590 (24%)
HSPD1	NP_002147.2	GroEL	28..548	CDD:239460	135/575 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810