Protein Alignment CCT3 and cct-2

DIOPT Version :10

• Sequence 1: NP_650572.2
• Gene: CCT3 / 42029
• FlyBaseID: FBgn0015019
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_741031.1
• Gene: cct-2 / 174421
• WormBaseID: WBGene00000378
• Length: 529
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 175/565 - (30%)
• Similarity: 283/565 - (50%)
• Gaps: 73/565 - (12%)

  Fly     7 PILVLSQNTKRESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLM----DPMGGIVMTNDGNAI 67
            |:.:|..|.:.|.|...:|.:.....||.|::::.|||:.|.|:|:    :..|||.:||||..|
 Worm     3 PVQILKDNAQEERGESARLSSFVGAIAIGDLVKSTLGPKGMDKILISGNPESAGGIKVTNDGATI 67

  Fly    68 LREITVQHPAAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREALE 132
            |:.|.|.:||||.:::::.|||.|||||||||.|||.|:|..||..:.|:|||..||..||.||
 Worm    68 LKSIGVDNPAAKVLVDMSMTQDHEVGDGTTSVTVLAAELLKEAEKLVNQRIHPQTIISGYRRAL- 131

  Fly   133 DIVGHLQSQL---SIQLDVKDKAKMADVVKACVGTKFIGKWSDLAVKIALDAVETVTLSENGRLE 194
               |..|..|   ||:.....:..:..:.:..:|:|.:.:..:...::|:|||  :.|..:|.|:
 Worm   132 ---GIAQESLKKSSIESGDNIRDDLLKIARTTLGSKILSQHKEHFAQLAVDAV--LRLKGSGNLD 191

  Fly   195 VDIKRYAKVEKIPGGAIEESCVLKGVMINKDVTHPKM--RRLIENPRIVLLDCSLEYKKGE---S 254
            .     .::.|..||::.||.:.:|.::.|   .|.|  .|.:|..:|::.:..::..|.:   |
 Worm   192 A-----IQIIKKLGGSMNESYLDEGFLLEK---LPGMFQPRRVEKAKILIANTPMDTDKVKVFGS 248

  Fly   255 QTNVE---IIGEQDFTRMLQIEEEFVQRICA---------DIIAVKPDLVFTEKGVSDLAQHYLL 307
            :..|:   .:.|.:....|:::|: |.:|.|         .:|...|:.:|.:..|..: :|
 Worm   249 RVRVDGVAKVAELEAAEKLKMKEK-VDKILAHNCNVFINRQLIYNYPEQLFADAKVMAI-EH--- 308

  Fly   308 KAGITAIRRLRKTDNLRIARACGATIVNRTEELTEKDVGTGAGLFEVKKIGDEYFTFVTECKEPK 372
             |....|.||        |...|..||:..:.......|: ..|.|...||::.....:..|..:
 Worm   309 -ADFEGIERL--------ALVLGGEIVSTFDSPQTAQFGS-CDLIEEIMIGEDRLLRFSGVKLGE 363

  Fly   373 ACTILLRGASKDILNETERNLQDALHVARNLVLEPRLVAGGGAVE--MAASQLLTRKQVKG---- 431
            ||:::||||::.||:|:||:|.|||.|....|.|.:.|||.||.|  |:::..:..::|.|
 Worm   364 ACSVVLRGATQQILDESERSLHDALCVLVTHVKESKTVAGAGASEILMSSAIAVEAQKVAGKEAL 428

  Fly   432 PYTAVAHALEIIPRTLAQNCGANTIRALTALRAKHASHTGDGVCAWGIDGESGEIVDMNVKNIWE 496
            ...|...||..:|..:..|.|.::...:|.|||:||    :|....|||.|.||:.|:....:.|
 Worm   429 AVEAFGRALAQLPTIICDNAGLDSAELVTRLRAEHA----NGRHNMGIDIEKGEVADVTKLGVIE 489

  Fly   497 PLAVKLQTYKTAVETAILLLRIDDIVSGSKKRGGNEPTNPAAMAQ 541
            ...|||....:|.|....:||:|||:..:          |.|.||
 Worm   490 SYNVKLCMVSSAAEATEQILRVDDIIKAA----------PRARAQ 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_650572.2	chap_CCT_gamma	7..528	CDD:274085	171/550 (31%)
cct-2	NP_741031.1	TCP1_beta	6..520	CDD:239452	170/556 (31%)