Protein Alignment CCT3 and CCT6B

DIOPT Version :9

• Sequence 1: NP_001189236.1
• Gene: CCT3 / 42029
• FlyBaseID: FBgn0015019
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_006575.2
• Gene: CCT6B / 10693
• HGNCID: 1621
• Length: 530
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 153/547 - (27%)
• Similarity: 278/547 - (50%)
• Gaps: 70/547 - (12%)

  Fly    14 NTKRE--SGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGNAILREITVQHP 76
            |:|.|  ..|.....||.|.:.:.||:||.|||:..:|||:...|.|.:|.|||.:|.|:.:|||
Human     8 NSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHP 72

  Fly    77 AAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYR----EALEDIVGH 137
            .|..:.::|..||:..||||||.:::.||:|..|:.::.:.:||.:|...:.    :|||
Human    73 TASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALE----- 132

  Fly   138 LQSQLSIQLDVKDKAKMADVVKACVGTKFIGKWSDLAVKIALDAVETVTLSENGRLEVDIKRYAK 202
            :..::.:..::|.|. :.||.:..:.||...:.:|:..::.:|:|..|
Human   133 VLEEVKVTKEMKRKI-LLDVARTSLQTKVHAELADVLTEVVVDSVLAV----------------- 179

  Fly   203 VEKIPGGAIE---------------ESCVLKGVMINKDVTHPKMRRLIENPRIVLLDCSLEYKKG 252
              :.||..|:               ::.:::|::::....||.|::.:|:..|::.:.||||:|.
Human   180 --RRPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKT 242

  Fly   253 ESQTNVEIIGEQDFTRMLQIEEEFVQ-----------RICADIIAVKPDLVFTEKGVSDLAQHYL 306
            |..:.......::..::::.|.:|::           ::||.  :.|..:|..:||:...:...|
Human   243 EVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQ--SNKGFVVINQKGIDPFSLDSL 305

  Fly   307 LKAGITAIRRLRKTDNLRIARACGATIVNRTEELTEKDVGTGAGLFEVKKIGDEYFTFVTECKEP 371
            .|.||.|:||.::.:..|::.|||...||..|:||...:| .|||.....:|:|.|||:.||..|
Human   306 AKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLG-HAGLVYEYTLGEEKFTFIEECVNP 369

  Fly   372 KACTILLRGASKDILNETERNLQDALHVARNLVLEPRLVAGGGAVEMAASQLLT--RKQVKG--- 431
            .:.|:|::|.:|..|.:.:..::|.|...:|.:.:..:|.|.||:|:|.::.|.  :..:||
Human   370 CSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRAR 434

  Fly   432 -PYTAVAHALEIIPRTLAQNCGANTIRALTALRAKHASHTGDGVCAWGIDGESGEIVDMNVKNIW 495
             ...|.|.||.|||:.||||.|.:....|..::|:|.    :.....|:|..:||.:......:|
Human   435 LGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHV----ESKQLVGVDLNTGEPMVAADAGVW 495

  Fly   496 EPLAVKLQTYKTAVETAILLLRIDDIV 522
            :...||.|...:....|..:|.:|:|:
Human   496 DNYCVKKQLLHSCTVIATNILLVDEIM 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_001189236.1	chap_CCT_gamma	7..528	CDD:274085	153/547 (28%)
		TCP1_gamma	7..524	CDD:239453	153/547 (28%)
CCT6B	NP_006575.2	chap_CCT_zeta	3..530	CDD:274088	153/547 (28%)
		TCP1_zeta	23..526	CDD:239458	149/532 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D207515at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820