Protein Alignment CCT3 and CCT2

DIOPT Version :9

• Sequence 1: NP_001189236.1
• Gene: CCT3 / 42029
• FlyBaseID: FBgn0015019
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_006422.1
• Gene: CCT2 / 10576
• HGNCID: 1615
• Length: 535
• Species: Homo sapiens
• Alignment Length: 560
• Identity: 169/560 - (30%)
• Similarity: 274/560 - (48%)
• Gaps: 78/560 - (13%)

  Fly     7 PILVLSQNTKRESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDP--MGGIVMTNDGNAILR 69
            |:.:.......|.....:|.:.....||.|::::.|||:.|.|:|:..  ...:::||||..||:
Human     8 PVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILK 72

  Fly    70 EITVQHPAAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREA---- 130
            .|.|.:||||.:::::|.||:|||||||||.|||.|:|..||..:.::|||..||..:|||
Human    73 NIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA 137

  Fly   131 ----LEDIVGHLQSQLSIQLDVKDKAKMADVVKACVGTKFIGKWSDLAVKIALDAVETVTLSENG 191
                |...|.|...      :||.:..:.::....:.:|.:....|...|:|::||  :.|..:|
Human   138 REALLSSAVDHGSD------EVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAV--LRLKGSG 194

  Fly   192 RLEVDIKRYAKVEKIPGGAIEESCVLKGVMINK--DVTHPKMRRLIENPRIVLLDCSLEYKKGES 254
            .||.     ..:.|..||::.:|.:.:|.:::|  .|..||.   |||.:|::.:..::..|
Human   195 NLEA-----IHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKR---IENAKILIANTGMDTDK--- 248

  Fly   255 QTNVEIIGEQ---DFT-RMLQIE-------EEFVQRI------C---ADIIAVKPDLVFTEKGVS 299
               ::|.|.:   |.| ::.:||       :|.|:||      |   ..:|...|:.:|...||
Human   249 ---IKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGV- 309

  Fly   300 DLAQHYLLKAGITAIRRLRKTDNLRIARACGATIVNRTEELTEKDVGTGAGLFEVKKIGDEYFTF 364
             :|..:...||:.           |:|...|..|.:..:......:|: ..|.|...||::....
Human   310 -MAIEHADFAGVE-----------RLALVTGGEIASTFDHPELVKLGS-CKLIEEVMIGEDKLIH 361

  Fly   365 VTECKEPKACTILLRGASKDILNETERNLQDALHVARNLVLEPRLVAGGGAVEM----AASQLLT 425
            .:.....:||||:||||::.||:|.||:|.|||.|....|.:.|.|.|||..||    |.:||..
Human   362 FSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLAN 426

  Fly   426 RKQVKGPYT--AVAHALEIIPRTLAQNCGANTIRALTALRAKHASHTGDGVCAWGIDGESGEIVD 488
            |...|....  :.|.||.::|..:|.|.|.::...:..|||.|:    :|....|:|...|.|.|
Human   427 RTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHS----EGNTTAGLDMREGTIGD 487

  Fly   489 MNVKNIWEPLAVKLQTYKTAVETAILLLRIDDIVSGSKKR 528
            |.:..|.|...||.|...:|.|.|.::||:|:|:..:.::
Human   488 MAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_001189236.1	chap_CCT_gamma	7..528	CDD:274085	169/558 (30%)
		TCP1_gamma	7..524	CDD:239453	169/554 (31%)
CCT2	NP_006422.1	TCP1_beta	11..527	CDD:239452	168/555 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810