Protein Alignment CCT3 and CCT7

DIOPT Version :9

• Sequence 1: NP_001189236.1
• Gene: CCT3 / 42029
• FlyBaseID: FBgn0015019
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_006420.1
• Gene: CCT7 / 10574
• HGNCID: 1622
• Length: 543
• Species: Homo sapiens
• Alignment Length: 553
• Identity: 172/553 - (31%)
• Similarity: 288/553 - (52%)
• Gaps: 36/553 - (6%)

  Fly     7 PILVLSQNTKRESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGNAILREI 71
            |:::|.:.|....|....:.||.|.:.||:.:||.|||:.|.|:::|..|...::|||..||:.:
Human     5 PVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLL 69

  Fly    72 TVQHPAAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREALEDIVG 136
            .|.|||||::::||::||.|||||||||.:||.|.|...:|::::.:||.:||||:|.|.:..|.
Human    70 DVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVN 134

  Fly   137 HLQSQLSIQLDVKDKAKMADVVKAC----VGTKFIGKWSDLAVKIALDAVETVTLSENGRLEVDI 197
            .:: ::::.:...||.:...:::.|    :.:|.|.:......|:.:|||  :.|.:..:|::
Human   135 KIK-EIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAV--MMLDDLLQLKM-- 194

  Fly   198 KRYAKVEKIPGGAIEESCVLKGVMINKDVTH------PKMRRLIENPRIVLLDCSLEYKKGESQT 256
               ..::|:.|||:|:|.::.||...|..::      ||.   ..||:|.||:..||.|..:...
Human   195 ---IGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKK---YHNPKIALLNVELELKAEKDNA 253

  Fly   257 NVEIIGEQDFTRMLQIEEEFVQRICADIIAVKPDLVFTEKGVSDLAQHYLLKAGITAIRRLRKTD 321
            .:.:...:|:..::..|...:......|......:|.::..:.|:|..|.....:....|:.:.|
Human   254 EIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRVPEED 318

  Fly   322 NLRIARACGATIVNRTEELTEKDVGTGAGLFEVKKIGDEYFTFVTECKEPKACTILLRGASKDIL 386
            ..|...|||.:|......|: .||.....:||..:||.|.:.|.|.|.:.|.||.:|||.::..:
Human   319 LKRTMMACGGSIQTSVNALS-ADVLGRCQVFEETQIGGERYNFFTGCPKAKTCTFILRGGAEQFM 382

  Fly   387 NETERNLQDALHVARNLVLEPRLVAGGGAVEMAASQLLT--RKQVKGPYT----AVAHALEIIPR 445
            .||||:|.||:.:.|..:....:||||||:||..|:.|.  .:.:.|...    |.|.|||||||
Human   383 EETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPR 447

  Fly   446 TLAQNCGANTIRALTALRAKHASHTGDGVCAWGIDGESGEIVDMNVKNIWEPLAVKLQTYKTAVE 510
            .|..|.|.:....|..|||:||    .|...:|:|..:.:|.|.....:|||..|::.....|.|
Human   448 QLCDNAGFDATNILNKLRARHA----QGGTWYGVDINNEDIADNFEAFVWEPAMVRINALTAASE 508

  Fly   511 TAILLLRIDDIVSGSKKRGGNEPTNPAAMAQGQ 543
            .|.|::.:|:.:    |...:....|.|..:|:
Human   509 AACLIVSVDETI----KNPRSTVDAPTAAGRGR 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT3	NP_001189236.1	chap_CCT_gamma	7..528	CDD:274085	168/536 (31%)
		TCP1_gamma	7..524	CDD:239453	168/532 (32%)
CCT7	NP_006420.1	TCP1_eta	5..525	CDD:239456	169/539 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	524..543		3/14 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810