DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10324 and SPP2

DIOPT Version :9

Sequence 1:	NP_650571.2	Gene:	CG10324 / 42028	FlyBaseID:	FBgn0038454	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_014791.1	Gene:	SPP2 / 854319	SGDID:	S000005674	Length:	185	Species:	Saccharomyces cerevisiae

Alignment Length:	153	Identity:	44/153 - (28%)
Similarity:	73/153 - (47%)	Gaps:	32/153 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 TESLEQRAARELISAIQNNGAEGLDDQ-----KLVLP-ALSAD----ELPLDGAKEATLDDYDNI 159
            |.||..:...::  .||:.....||::     |||:. :.:||    :.||  .:..|..:|:.:
Yeast    40 TASLSHKPQSKI--KIQSIDKFDLDEESSSKKKLVIKLSENADTKKNDAPL--VEYVTEKEYNEV 100

  Fly   160 PIQQFGLAMLRGMGW-VDPPPKKKG------SGPIDDAPFLRPKGMGLGA--DKALKPKALLVQP 215
            |:::||.|:|||||| .|.....||      :..:.:...:.|.|:|:||  :||:..:.....|
Yeast   101 PVEEFGDALLRGMGWESDSEQDSKGDKTQSRNKDVSNVSQIHPDGLGIGAKLNKAINVEEASFMP 165

  Fly   216 EKNEVLEIKKQAYVRILGGKQKD 238
                |::|.|     |.|.|..|
Yeast   166 ----VVKIDK-----ITGTKVDD 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10324	NP_650571.2	DUF2207	<67..>137	CDD:303056	10/37 (27%)
		G-patch_2	146..208	CDD:289427	22/70 (31%)
		KOW_GPKOW_A	227..282	CDD:240516	4/12 (33%)
SPP2	NP_014791.1	G-patch_2	93..151	CDD:372242	19/57 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345214
Domainoid	1	1.000	40	1.000	Domainoid score	I3261
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004009
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6078
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960