Protein Alignment Arl6IP1 and RETREG2

DIOPT Version :10

• Sequence 1: NP_650570.1
• Gene: Arl6IP1 / 42027
• FlyBaseID: FBgn0038453
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_077269.3
• Gene: RETREG2 / 79137
• HGNCID: 28450
• Length: 543
• Species: Homo sapiens
• Alignment Length: 185
• Identity: 31/185 - (16%)
• Similarity: 71/185 - (38%)
• Gaps: 22/185 - (11%)

  Fly    19 LEPFRTAIVGAYGVLTWEKQYYAGVVFGVISCLYLVLWYLDLSLITLLSLLGVISILLNYAFPMV 83
            |..:...:..|..:|.|||..::.|....::.|:   |.|..|.:....||.| |:|..:...:.
Human    60 LRGWEAVLAAAQRLLVWEKPLHSLVTAAALNGLF---WLLSSSSLRPFFLLSV-SLLAYFLLDLW 120

  Fly    84 SRLIFGGVNWDGDQEAKFE----------------DVCGQVCAVKGSLVVWYEYL--FNERKSTV 130
            .......|:....:|...:                ::|..:.....:..:..:.|  :..:....
Human   121 QPRFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKRQNPAQ 185

  Fly   131 FVIVMSLGLLAMAWIGAIINNLLLMYLATLLILMWPGLQNKDIFKAITQRASKII 185
            |.:.:..|...:|.:|..:..:::.|:..|.||:||.:...::.:.:..|...::
Human   186 FCVRVCSGCAVLAVLGHYVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLL 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arl6IP1	NP_650570.1	Arl6IP1_RETR3-like	30..194	CDD:425403	29/174 (17%)
RETREG2	NP_077269.3	RETR2_RHD	51..249	CDD:411700	31/185 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	254..287
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	336..394
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	411..486
		LIR motif. /evidence=ECO:0000305|PubMed:26040720	490..495
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	504..543