DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl6IP1 and retreg2

DIOPT Version :9

Sequence 1:	NP_001262647.1	Gene:	Arl6IP1 / 42027	FlyBaseID:	FBgn0038453	Length:	197	Species:	Drosophila melanogaster
Sequence 2:	XP_005160348.1	Gene:	retreg2 / 564232	ZFINID:	ZDB-GENE-061215-128	Length:	546	Species:	Danio rerio

Alignment Length:	231	Identity:	45/231 - (19%)
Similarity:	92/231 - (39%)	Gaps:	49/231 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AASQVDQKRALNKLKHDLEPFRTAIVGAYGVLTWEKQYYAGVVFGVISCLYL--VLWYLDLSLIT 64
            |..:.:.:|...:|:..|.....|:|....:|.||:..::     :|:.|.|  :.|.|..:.:.
Zfish    25 AEEEPELRRLRERLRGCLSQCEPAVVLLQRLLVWERPLHS-----IIAALALNTLFWLLSSTSLR 84

  Fly    65 LLSLLGVISILLNY------AFPMVSRLIFGGVNWDG-----DQEAKFEDVCGQVCAVKG----- 113
            .|.||.|..|.|..      ..|.::.       |..     ::||..:.:  ::.:|:.
Zfish    85 PLFLLSVFLIGLTLLERWKDKLPQITA-------WRPEASVIEREALSDQL--RLLSVEELSHHL 140

  Fly   114 -------SLVVWYEYLFNERKSTVFVIVMSLGLLAMAWIGAIINNLLLMYLATLLILMWPGLQNK 171
                   ||.:.....:..:....|.|:|..|...||.:|..|..:::.|:..|.:|:||.:...
Zfish   141 AESYLTFSLYIQEMLQYKRQNHGKFCIMMCSGCFTMAVVGHYIPGVMITYIILLSVLLWPLVVYH 205

  Fly   172 DIFKAITQRASKII----------NEKIQCGKRKLQ 197
            ::.:.:..|...|:          .::.:..|||::
Zfish   206 ELIQKMYTRLEPILMKLDYSMKGDTQRRKYDKRKMK 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl6IP1	NP_001262647.1	Reticulon	29..187	CDD:251305	36/192 (19%)
retreg2	XP_005160348.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR20952
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100