DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl6IP1 and ARL6IP1

DIOPT Version :9

Sequence 1:	NP_001262647.1	Gene:	Arl6IP1 / 42027	FlyBaseID:	FBgn0038453	Length:	197	Species:	Drosophila melanogaster
Sequence 2:	NP_055976.1	Gene:	ARL6IP1 / 23204	HGNCID:	697	Length:	203	Species:	Homo sapiens

Alignment Length:	183	Identity:	53/183 - (28%)
Similarity:	102/183 - (55%)	Gaps:	2/183 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LKHDLEPFRTAIVGAYGVLTWEKQYYAGVVFGVISCLYLVLWYLDLSLITLLSLLGVISILLNYA 79
            |:..|:.:...::.|..||.||:.::...:.||:|.::|:::|||.|:::.:|...:...|.:|.
Human    19 LEEQLQGWGEVMLMADKVLRWERAWFPPAIMGVVSLVFLIIYYLDPSVLSGVSCFVMFLCLADYL 83

  Fly    80 FPMVSRLIFGGVNWDGDQEAKFEDVCGQVCAVKGSLVVWYEYLF--NERKSTVFVIVMSLGLLAM 142
            .|:::..|||...|..:|:.:|.::|..:...:...|.|::.||  .|.|..::.:.|.:.|.|:
Human    84 VPILAPRIFGSNKWTTEQQQRFHEICSNLVKTRRRAVGWWKRLFTLKEEKPKMYFMTMIVSLAAV 148

  Fly   143 AWIGAIINNLLLMYLATLLILMWPGLQNKDIFKAITQRASKIINEKIQCGKRK 195
            ||:|..::||||.||....:|:.|||....|.......|.:.||:.::..::|
Human   149 AWVGQQVHNLLLTYLIVTSLLLLPGLNQHGIILKYIGMAKREINKLLKQKEKK 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl6IP1	NP_001262647.1	Reticulon	29..187	CDD:251305	49/159 (31%)
ARL6IP1	NP_055976.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144573
Domainoid	1	1.000	105	1.000	Domainoid score	I6641
eggNOG	1	0.900	-	-		E1_2CN40
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41008
Inparanoid	1	1.050	105	1.000	Inparanoid score	I4948
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45227
OrthoDB	1	1.010	-	-		D1268983at2759
OrthoFinder	1	1.000	-	-		FOG0009822
OrthoInspector	1	1.000	-	-		oto90545
orthoMCL	1	0.900	-	-		OOG6_108648
Panther	1	1.100	-	-	LDO	PTHR20952
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4472
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800