DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nonA-l and ML4

DIOPT Version :9

Sequence 1:	NP_001262646.1	Gene:	nonA-l / 42026	FlyBaseID:	FBgn0015520	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_196346.1	Gene:	ML4 / 830620	AraportID:	AT5G07290	Length:	907	Species:	Arabidopsis thaliana

Alignment Length:	402	Identity:	96/402 - (23%)
Similarity:	151/402 - (37%)	Gaps:	85/402 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 VANNSH-QKQINESPKPAAGNVPAKNNELSAGG--GGQNQPNHSNKGQGNQ-GDQGEQGNQGPNF 162
            |...|| .:.|..:|:...|.:  |||.:..||  ...|.|..|......| ..|.......|:|
plant    11 VPTPSHFHEDIRITPEKQFGFM--KNNPMPEGGVDRSSNLPTSSWTSDSYQLSQQSSLSGALPSF 73

  Fly   163 --RGR-------------------------------------GGGPNQPNQNANQEQSNGYPGNQ 188
              .||                                     .....:|:::..:.::... ||.
plant    74 IPNGRTTTNDTHWESSLFSSSLSDLFSRKLRLPRSDKLAFMSANREEEPSESLEEMEAQTI-GNL 137

  Fly   189 GDNKGGQGQRGAGGGKHQRGNRSRRSGGSGI----MNSSMGGGGQRGEDF-FIAQRLLDISGPTH 248
            ..::........|.|.|    :||.:||..:    :.||:||....|:.| .::||  |....::
plant   138 LPDEDDLFAEVVGEGVH----KSRANGGDDLDDCDLFSSVGGMELDGDVFSSVSQR--DGKRGSN 196

  Fly   249 ELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYY--Q 311
            .....|.| ..:.:.| .|:|.|:.|...|.:|..:||.:|::..:.: ..||..|:.:.||  :
plant   197 VSTVAEHP-QGEILSR-ILFVRNVDSSIEDCELGVLFKQFGDVRALHT-AGKNRGFIMVSYYDIR 258

  Fly   312 NAEKAKRALDGSLRKGRVLRVRF----------APNAIVRVTNLNQFVSNELLHQSFEIFGPIER 366
            .|:||.|||.|.|.:||.|.:|:          :....:.|.||:..:|||.||..|..:|.|..
plant   259 AAQKAARALHGRLLRGRKLDIRYSIPKENPKENSSEGALWVNNLDSSISNEELHGIFSSYGEIRE 323

  Fly   367 AVICVDDRGKHTGEGI-VEFAKKSSASACLRLCNE-KCFFLTASLRPCLVE-----PMEVNNDND 424
            .     .|..|....: :||.....|...|:..|. :.......|.|...|     |...::|.:
plant   324 V-----RRTMHENSQVYIEFFDVRKAKVALQGLNGLEVAGRQLKLAPTCPEGTSFWPQFASDDGE 383

  Fly   425 -GLPDKTLNKKS 435
             |||....|..|
plant   384 GGLPKMAFNNLS 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nonA-l	NP_001262646.1	RRM1_p54nrb_like	264..334	CDD:240778	26/71 (37%)
		RRM2_p54nrb_like	339..418	CDD:240779	22/85 (26%)
		NOPS_NONA_like	409..508	CDD:240580	10/33 (30%)
		OmpH	<479..578	CDD:281871
		DUF4472	479..559	CDD:291409
ML4	NP_196346.1	RRM1_MEI2_like	210..286	CDD:240968	27/77 (35%)
		RRM2_MEI2_EAR1_like	295..364	CDD:240722	18/73 (25%)
		RRM	655..898	CDD:223796
		RRM_2	741..837	CDD:112856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910