DRSC/TRiP Functional Genomics Resources

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Protein Alignment nonA-l and Rbm15

DIOPT Version :9

Sequence 1:NP_001262646.1 Gene:nonA-l / 42026 FlyBaseID:FBgn0015520 Length:630 Species:Drosophila melanogaster
Sequence 2:XP_003749428.1 Gene:Rbm15 / 684233 RGDID:1592713 Length:962 Species:Rattus norvegicus


Alignment Length:720 Identity:134/720 - (18%)
Similarity:225/720 - (31%) Gaps:252/720 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 SLNSSPLPQRQQRGNSTN----------------KNLGKPTPPKLNAASDGNPAEKKARLGGNTQ 57
            |....|||:|..|....:                .:|.:|:..|   ..:.:|.:.|...||...
  Rat     3 SAGREPLPRRSPRWRRASPLCETSAGWRVSQLRRDDLRRPSTMK---GKERSPVKPKRSRGGEDS 64

  Fly    58 NGGG-----VAGGGGTGGGGGG----GGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINE 113
            :..|     :.|.||:.|...|    ||:...:...::.:|||::.     :.....|...:::.
  Rat    65 SSRGERSKKLGGSGGSNGSSSGKTDSGGSRRSLHLDKSSSRGGSRE-----YDTGGGSSSSRLHS 124

  Fly   114 SPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQ 178
            ...|:..|        |:|||   :...|::|.|     ||..:.|......|||.....:....
  Rat   125 YSSPSTKN--------SSGGG---ESRSSSRGGG-----GESRSSGAASSAPGGGDGVEYKTLKI 173

  Fly   179 EQSNGYPGNQGDNKG---------------------GQGQ-----------RGAGGGKHQRG--- 208
            .:......::....|                     |.|.           ..|...||.||   
  Rat   174 SELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLV 238

  Fly   209 ---------------NRSRR-------SGGSGIMNSSM--------GGGGQRG----------ED 233
                           .|||.       :..|.::.||:        ||||||.          .|
  Rat   239 LYDRPLKIEAVYVSRRRSRSPLDKDTYAPSSSVVGSSVGSHRHAPGGGGGQRSLSPGGAALGYRD 303

  Fly   234 FFIAQRLLDISGPTHELPPIELP------TDNKFVGRNR-------------------------- 266
            :.:.|..|....|.   ||..||      .|..|..|.|                          
  Rat   304 YRLQQLALGRLPPP---PPPPLPRELERERDYPFYDRVRPAYSLEPRVGAGAGAAPFREVDEISP 365

  Fly   267 ---------LYVGNLTSDTTDDDLREMFKPYGEIGDI-FSNPEKNFT----FLRLDYYQNAEKAK 317
                     |::|||....|::|||..|..:|.|.:: ...|.:..|    ||:.:....:.:||
  Rat   366 EDDQRANRTLFLGNLDITVTENDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAK 430

  Fly   318 RALDGSLRKGRVLRVRF---APNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTG 379
            .|:.|.:.....:::.:   .|...:.|..|..:|....|.:.|:.||.| |.:    |..|...
  Rat   431 IAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTI-RTI----DYRKGDS 490

  Fly   380 EGIVEFAKKSSASAC---------------LRL--CNEKCFFLTASLRPCLVEPMEVNNDNDG-- 425
            ...:::....:|.|.               ||:  .:.:..:....|:|..:...|:..|..|  
  Rat   491 WAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVTDTFGHR 555

  Fly   426 LPDKTLNKKS----LEFR-------------------HERSVGPRFACLNSFEHEYGSRWKQLHD 467
            .||...:.:.    |.:|                   .|||.....:.:.::|            
  Rat   556 APDPLRSARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSARAATSAVTAYE------------ 608

  Fly   468 LFKSKQDSLKRE---LKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAE 529
                ..|||.|.   ..::.|:.:..:..:|.:.....|.:|...|.||          |..:::
  Rat   609 ----PLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLD----------RSPESD 659

  Fly   530 EIRKR 534
            ..||:
  Rat   660 RPRKQ 664

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nonA-lNP_001262646.1 RRM1_p54nrb_like 264..334 CDD:240778 21/109 (19%)
RRM2_p54nrb_like 339..418 CDD:240779 17/95 (18%)
NOPS_NONA_like 409..508 CDD:240580 21/126 (17%)
OmpH <479..578 CDD:281871 10/59 (17%)
DUF4472 479..559 CDD:291409 10/59 (17%)
Rbm15XP_003749428.1 RRM1_RBM15 168..250 CDD:240997 8/81 (10%)
RRM2_RBM15 366..452 CDD:240999 19/85 (22%)
RRM3_RBM15 455..527 CDD:241001 15/76 (20%)
SPOC 789..925 CDD:285043
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166347816
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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