Protein Alignment nonA-l and RBM15

DIOPT Version :9

• Sequence 1: NP_001262646.1
• Gene: nonA-l / 42026
• FlyBaseID: FBgn0015520
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_073605.4
• Gene: RBM15 / 64783
• HGNCID: 14959
• Length: 977
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 93/476 - (19%)
• Similarity: 152/476 - (31%)
• Gaps: 169/476 - (35%)

  Fly    13 SPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGA 77
            ||:..::.||...:.:.|                |:..:|||:     |.:.|..:|....|||:
Human    51 SPVKAKRSRGGEDSTSRG----------------ERSKKLGGS-----GGSNGSSSGKTDSGGGS 94

  Fly    78 TGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHS 142
            ...:...::.:|||::.     :.....|...:::....|:..|        |:|||   :...|
Human    95 RRSLHLDKSSSRGGSRE-----YDTGGGSSSSRLHSYSSPSTKN--------SSGGG---ESRSS 143

  Fly   143 NKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKG-------------- 193
            ::|.|     ||..:.|......|||.....:.....:......::....|
Human   144 SRGGG-----GESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVK 203

  Fly   194 -------GQGQ-----------RGAGGGKHQRGNR--------------SRRSGGS--------- 217
                   |.|.           ..|...||.||..              |||...|
Human   204 ISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDTYPP 268

  Fly   218 --GIMNSSM--------GGGGQRG----------EDFFIAQRLLDISGPTHELPPIELPTDNK-- 260
              .::.:|:        ||||||.          .|:.:.|..|....|.   ||..||.|.:
Human   269 SASVVGASVGGHRHPPGGGGGQRSLSPGGAALGYRDYRLQQLALGRLPPP---PPPPLPRDLERE 330

  Fly   261 ----FVGRNR-----------------------------------LYVGNLTSDTTDDDLREMFK 286
                |..|.|                                   |::|||....|:.|||..|.
Human   331 RDYPFYERVRPAYSLEPRVGAGAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFD 395

  Fly   287 PYGEIGDI-FSNPEKNFT----FLRLDYYQNAEKAKRALDGSLRKGRVLRVRF---APNAIVRVT 343
            .:|.|.:: ...|.:..|    ||:.:....:.:||.|:.|.:.....:::.:   .|...:.|.
Human   396 RFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVG 460

  Fly   344 NLNQFVSNELLHQSFEIFGPI 364
            .|..:|....|.:.|:.||.|
Human   461 GLGPWVPLAALAREFDRFGTI 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nonA-l	NP_001262646.1	RRM1_p54nrb_like	264..334	CDD:240778	21/109 (19%)
		RRM2_p54nrb_like	339..418	CDD:240779	8/26 (31%)
		NOPS_NONA_like	409..508	CDD:240580
		OmpH	<479..578	CDD:281871
		DUF4472	479..559	CDD:291409
RBM15	NP_073605.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..167		34/157 (22%)
		RRM1_RBM15	169..251	CDD:409969	8/81 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..298		8/41 (20%)
		RRM2_RBM15	367..453	CDD:409971	19/85 (22%)
		RRM3_RBM15	456..528	CDD:409973	8/26 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	555..778
		SF-CC1	624..>736	CDD:273721
		SPOC	781..954	CDD:400205
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	865..884

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154199
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930