DRSC/TRiP Functional Genomics Resources

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Protein Alignment nonA-l and Raver2

DIOPT Version :10

Sequence 1:NP_536740.1 Gene:nonA-l / 42026 FlyBaseID:FBgn0015520 Length:630 Species:Drosophila melanogaster
Sequence 2:NP_898845.1 Gene:Raver2 / 242570 MGIID:2443623 Length:673 Species:Mus musculus


Alignment Length:306 Identity:78/306 - (25%)
Similarity:126/306 - (41%) Gaps:48/306 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   213 RSGGSGIMNSSMG-GGGQRGEDFFIAQRLLDISGPTHELPPIELPT-----DNKFVGRNRLYVGN 271
            |.||:|...|..| ..|..||....|.|    .|....|.|.|:..     ..:...|.::.|.|
Mouse     4 RGGGAGGAGSGSGPSAGTAGEAAEPALR----PGEVAALHPQEVAARLQRMRRELSNRRKILVKN 64

  Fly   272 LTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDG----SLRKGRVLRV 332
            |..|::..::.|:.:.| |:...:.:..|...|:.|   .|.|:|:.|:..    |.| ||.|.|
Mouse    65 LPQDSSSQEVHELLQDY-ELKYCYVDRNKRTAFVTL---LNGEQAQSAIQRFHQFSFR-GRELTV 124

  Fly   333 RFAP-NAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDD-RGKHTGEGIVEFAKKS-SASAC 394
            :..| :|::.:|||....:.|...:....:|.|||..:...: .|...|.|.||:.||. :|.|.
Mouse   125 QLQPTDALLCITNLPISFTLEEFEELVRAYGNIERCFLVYSEVTGHSKGYGFVEYMKKDFAAKAR 189

  Fly   395 LRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYG 459
            |.|...:   :.||  ....:.|:||.    |..:.::.|.|             |::....:| 
Mouse   190 LELLGRQ---MGAS--ALFAQWMDVNL----LASELIHSKCL-------------CIDKLPSDY- 231

  Fly   460 SRWKQLHDLFKSKQDSLKRELKMEEDKLE---AQMEYARYEQETEL 502
            |..::|..||......:..:|..:|....   |.:||:..|...|:
Mouse   232 SDSEELLQLFSGIHKPVFCQLAQDEGSHGGGFAVVEYSTAEHAEEV 277

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nonA-lNP_536740.1 PRK12678 3..>219 CDD:237171 3/5 (60%)
Med15 <90..>191 CDD:312941
RRM1_p54nrb_like 264..334 CDD:409769 21/73 (29%)
RRM2_p54nrb_like 339..418 CDD:409770 21/80 (26%)
NOPS_NONA_like 409..508 CDD:240580 19/97 (20%)
APG6_N <477..555 CDD:465452 7/29 (24%)
Raver2NP_898845.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..34 11/33 (33%)
RRM1_RAVER2 59..128 CDD:410065 20/73 (27%)
RRM2_RAVER2 132..208 CDD:410067 21/80 (26%)
RRM3_RAVER2 218..314 CDD:410069 15/74 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 481..549
Blue background indicates that the domain is not in the aligned region.

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