Protein Alignment nonA-l and LOC1271533

DIOPT Version :10

• Sequence 1: NP_536740.1
• Gene: nonA-l / 42026
• FlyBaseID: FBgn0015520
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_061496966.1
• Gene: LOC1271533 / 1271533
• VectorBaseID: AGAMI1_013169
• Length: 644
• Species: Anopheles gambiae
• Alignment Length: 655
• Identity: 293/655 - (44%)
• Similarity: 379/655 - (57%)
• Gaps: 104/655 - (15%)

  Fly     1 MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNG------ 59
            |:.|||: .:|.||||||.|:         :|     :....|.|..    :.||.|.|
Mosquito     1 MDVAVKQ-EINGSPLPQRPQQ---------QP-----HGGGGGGPGP----MQGNNQAGPDQHGP 46

  Fly    60 ---GGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGN 121
               ||..|.||.||.||.||..|          .||:|.||..   .|||..:|    ..|....
Mosquito    47 GGPGGPGGPGGPGGPGGPGGPGG----------PGNKNMNRNN---RNNSKNRQ----SMPNRNR 94

  Fly   122 VPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPG 186
            .|..|    |||||.| || :|.|.||    ...||.|.|.:..||....|||:.|:
Mosquito    95 GPGGN----AGGGGGN-PN-NNGGPGN----NRPGNNGGNPQQMGGEDFGPNQHQNR-------- 141

  Fly   187 NQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELP 251
                           ||.|:..||     |...|::|.|...:.||.:||.::|..::||..|:|
Mosquito   142 ---------------GGMHRGNNR-----GGNDMDNSFGDRRRGGEAYFINEKLRQLAGPLFEIP 186

  Fly   252 PIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKA 316
            ||| ..|.||.|||||||||||:|.|:::|.:|||.||||.::|.|.|||:.|:|:||..|||.|
Mosquito   187 PIE-AQDVKFSGRNRLYVGNLTNDVTEEELVDMFKVYGEISEVFMNKEKNYAFVRVDYLSNAEAA 250

  Fly   317 KRALDGSLRKGRVLRVRFAPNA-IVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGE 380
            ||.|||:.||.||||||||||| .:||.||..:|:||||:::||:|||:||||:.||:|||.|||
Mosquito   251 KRGLDGTTRKNRVLRVRFAPNATAIRVKNLTPYVTNELLYKAFEVFGPLERAVVQVDERGKPTGE 315

  Fly   381 GIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVG 445
            |||||..|..|.|.:|.|.|||:||||||||.:|||....:||||||:|:||||..:|...|..|
Mosquito   316 GIVEFKNKPGAMAAIRYCTEKCYFLTASLRPVIVEPYTYQDDNDGLPEKSLNKKQNDFLKARQQG 380

  Fly   446 PRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKR 510
            ||||...|||.|||.|||.:|:|||.|.:|||||:.|||:|||||||||||||||||||::|::|
Mosquito   381 PRFAEHGSFEFEYGQRWKHMHELFKQKAESLKREMIMEEEKLEAQMEYARYEQETELLREQLRQR 445

  Fly   511 ELDNERMKLEWEMREKQAEEIRKREE----EYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNM 571
            |:|.:|.|.||||:|:|.:|.|:|.:    ..:.....::.|.:|::..||:||::.||.:::|:
Mosquito   446 EMDRDRQKAEWEMKERQVQEARQRNDIQIKTELEEMTTRIKRSDEELHRRQKENNMFMQNRQMNI 510

  Fly   572 ILDQQE-----------GFGGSNSGFE---HFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHI 622
            |..||:           |.||..||.:   :||...:|.|.........|.||..|. ||....:
Mosquito   511 IDPQQQMNDMGGMGGSGGDGGGGSGIDNRRNFDMMNQVVGGGGGGGGGGGGGGNGNF-GNMEPTV 574

  Fly   623 DSWGH 627
            ..:.|
Mosquito   575 RDYDH 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nonA-l	NP_536740.1	PRK12678	3..>219	CDD:237171	70/224 (31%)
		Med15	<90..>191	CDD:312941	34/100 (34%)
		RRM1_p54nrb_like	264..334	CDD:409769	45/69 (65%)
		RRM2_p54nrb_like	339..418	CDD:409770	50/78 (64%)
		NOPS_NONA_like	409..508	CDD:240580	65/98 (66%)
		APG6_N	<477..555	CDD:465452	42/81 (52%)
LOC1271533	XP_061496966.1	None