Protein Alignment Fas1 and Postn

DIOPT Version :10

• Sequence 1: NP_001097814.1
• Gene: Fas1 / 42025
• FlyBaseID: FBgn0285925
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001355607.1
• Gene: Postn / 50706
• MGIID: 1926321
• Length: 838
• Species: Mus musculus
• Alignment Length: 763
• Identity: 163/763 - (21%)
• Similarity: 275/763 - (36%)
• Gaps: 210/763 - (27%)

  Fly     1 MLNAAALLLALLCAANAAAAADLADKL--------RDDSE------------------------- 32
            :|...||||..||..|.|.|....||:        ||...
Mouse     4 LLPLYALLLLFLCDINPANANSYYDKVLAHSRIRGRDQGPNVCALQQILGTKKKYFSSCKNWYQG 68

  Fly    33 -----------------LSQSTAKSLRRLMPV-RFYSLL-----ESNQIANSTLSLR-------S 67
                             :.....|....:||: ..|..|     .:.|..:....||       |
Mouse    69 AICGKKTTVLYECCPGYMRMEGMKGCPAVMPIDHVYGTLGIVGATTTQHYSDVSKLREEIEGKGS 133

  Fly    68 CTIFVPTNEAFQRYKS------------KTAHVLY-HITTEAYTQKRLPN-TVSSDMAGNPPLYI 118
            .|.|.|:|||::...|            :..:.|: |:..:....|.|.: .|...|..|..|:|
Mouse   134 YTYFAPSNEAWENLDSDIRRGLENNVNVELLNALHSHMVNKRMLTKDLKHGMVIPSMYNNLGLFI 198

  Fly   119 TKNSNGDIFVNNARIIPSLSVETNSDGKRQIMHIIDEVLEPLTVKAGHSDTPNNPNALKFLKNAE 183
            ....||.:.||.||:|....:.||.     ::|:||.||           |....:...||:..:
Mouse   199 NHYPNGVVTVNCARVIHGNQIATNG-----VVHVIDRVL-----------TQIGTSIQDFLEAED 247

  Fly   184 EFNVDNIGVRTYR-SQVTMAKKESVYDAAGQHTFLVPVDEGFKLSARSSL-------VDGKVIDG 240
            :.:       ::| :.:|....||: ...|..|...|.:|.|:...|..|       |..:.:..
Mouse   248 DLS-------SFRAAAITSDLLESL-GRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMK 304

  Fly   241 HVIPNTVIFTAAAQHDDPKASAAFEDLLKVTVSFFKQKNGKMYVKSNTI----VGDAKHRVGVVL 301
            :.|.||:..:.|.     ...|.||.:                 :.|||    .||:....|:.:
Mouse   305 YHILNTLQCSEAI-----TGGAVFETM-----------------EGNTIEIGCEGDSISINGIKM 347

  Fly   302 AEIVKANIPVSNGVVHLIHRPLMIIDTTVTQFLQENAENGALRKFYEVIMDNGGAVLDDINSLT- 365
              :.|.:|...|||:|||..  ::|..:..|.::...:...  .|.:::...|.|     :||.
Mouse   348 --VNKKDIVTKNGVIHLIDE--VLIPDSAKQVIELAGKQQT--TFTDLVAQLGLA-----SSLKP 401

  Fly   366 --EVTILAPSNEAWNSSNINNVLRDRNKMRQILNMHIIKDRLNVDKIRQKNANLIAQVPTVNNNT 428
              |.|:|||.|.|::...::   .|:..::.||..||:|.::.:..:  .|..::..:.......
Mouse   402 DGEYTLLAPVNNAFSDDTLS---MDQRLLKLILQNHILKVKVGLSDL--YNGQILETIGGKQLRV 461

  Fly   429 FLYFNVRGEGSDTVITVEGGGVNATVIQADVAQTNGYVHIIDHVLGVPYTTVLGKLESDPMMSDT 493
            |:|        .|.|.:|    |:.:::......||.:||...::.....::..||..|...|..
Mouse   462 FVY--------RTAICIE----NSCMVRGSKQGRNGAIHIFREIIQPAEKSLHDKLRQDKRFSIF 514

  Fly   494 YKMGKFSHFNDQLNNTQ-RRFTYFVPRDKGWQKTELDYPSAHKKLFMADFSYHSKSILERHLAIS 557
            ..:.:.:...|.|  || ..:|.|.|.:.                     ::...:..||.|.|.
Mouse   515 LSLLEAADLKDLL--TQPGDWTLFAPTND---------------------AFKGMTSEERELLIG 556

  Fly   558 DKEYTMKDLVKFSQESGSVILPTFRDSLSIRVEEEAGRYVIIWNYKKIN---------VYRPDVE 613
            ||. .:::::.:....|..|...|...::..::...|..:.:   |.:|         ....|:.
Mouse   557 DKN-ALQNIILYHLTPGVYIGKGFEPGVTNILKTTQGSKIYL---KGVNETLLVNELKSKESDIM 617

  Fly   614 CTNGIIHVIDYPLLEEKDVVVAGGSYLPESSICIILANLIMITVAKFL 661
            .|||:|||:| .||...|:.| |...|.|     :|..||.....||:
Mouse   618 TTNGVIHVVD-KLLYPADIPV-GNDQLLE-----LLNKLIKYIQIKFV 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fas1	NP_001097814.1	Fasciclin	49..159	CDD:396845	36/135 (27%)
		FAS1	215..324	CDD:214719	28/119 (24%)
		FAS1	368..476	CDD:214719	23/107 (21%)
		Fasciclin	488..627	CDD:396845	28/148 (19%)
Postn	NP_001355607.1	Fasciclin	111..232	CDD:396845	32/125 (26%)
		Fasciclin	247..369	CDD:396845	33/155 (21%)
		Fasciclin	384..496	CDD:396845	29/135 (21%)
		Fasciclin	509..632	CDD:396845	30/150 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	811..838