Protein Alignment Fas1 and tgfbi

DIOPT Version :10

• Sequence 1: NP_001097814.1
• Gene: Fas1 / 42025
• FlyBaseID: FBgn0285925
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_878282.1
• Gene: tgfbi / 321421
• ZFINID: ZDB-GENE-030131-73
• Length: 677
• Species: Danio rerio
• Alignment Length: 595
• Identity: 134/595 - (22%)
• Similarity: 237/595 - (39%)
• Gaps: 140/595 - (23%)

  Fly    67 SCTIFVPTNEAFQRYKSKTAHVL-------------YHITTEAYTQKRLPNTVS-SDMAGNPPLY 117
            |.|.|.|:|||:....::....|             ||:..:..|.:.|.:..| |.|..:..::
Zfish   130 SFTFFAPSNEAWAPLPTEILDALVSNVNIELLNALHYHMINKRLTSEDLKHGSSFSSMHQDFDVH 194

  Fly   118 ITKNSNGDIFVNNARIIPSLSVETNSDGKRQIMHIIDEVLEPLTVKAGHSDTPNNPNALKFLKNA 182
            |...|||.:.||.||:     |:|:......|:|::|.|:..:|         |:.|::
Zfish   195 IHHYSNGIVTVNCARL-----VKTDQHATNGIVHVVDRVITAIT---------NDVNSI------ 239

  Fly   183 EEFNVDNIGVRTYRSQVTMAKKESVYDAAGQHTFLVPVDEGFKLSARSSLVDGKVIDGHVIPNTV 247
              .:.|: .:.|.|:.|..|...::.:..|.:|...|.:|.|:               .:.|:|:
Zfish   240 --IDTDD-DLDTLRTAVAAAGLTTLLENQGSYTIFAPTNEAFE---------------KIPPDTL 286

  Fly   248 IFTAAAQHDDPKASAAFEDLLKVTVSFFKQKNGKMYVKSNTIVGDAKHRV-GVVL---------- 301
            .....    ||   .|.:|||    :|...||  ::...:.:.|.....: |.:|
Zfish   287 TRILG----DP---VALKDLL----NFHILKN--LHCSESIVAGTPLETLQGTMLEVGCDGEDLT 338

  Fly   302 ----AEIVKANIPVSNGVVHLIHRPLMIIDTTVTQFLQENAENGALRKFYEVIMDNGGAVLDDIN 362
                |.:.:.:...:|||||.|:. |:|.|:..|  |.|.||...:....::..|.|  :.|.:.
Zfish   339 INGKAVVTQKDKLGTNGVVHYINE-LLIPDSAKT--LLELAEGSVVTTAAKLFKDAG--LNDHLV 398

  Fly   363 SLTEVTILAPSNEAWNSSNINNVLRDRN-----KMRQILNMHIIKDRLNVDKIRQKNANLIAQVP 422
            ....||:|||.|||:         :|::     .|:::|..||:|     :|...|:.....::.
Zfish   399 GSESVTLLAPLNEAF---------KDKSFAMTPDMKKLLRNHILK-----EKFSSKSLYHGQELE 449

  Fly   423 TVNNNTFLYFNVRGEGSDTVITVEGGGVNATVIQADVAQTNGYVHIIDHVLGVPYTTVLGKLESD 487
            |:.......|..|..     :.:|    ||.:...|.......:.::|.:|..|..||:..|::|
Zfish   450 TLGGLKLRVFVFRNN-----LCIE----NACIAAHDKNGRYANMFLVDSILTPPQGTVMDVLKAD 505

  Fly   488 ----PMMSDTYKMGKFSHFNDQLNNTQRRFTYFVPRDKGWQKTELDYPSAHKKLFMADFSYHSKS 548
                .::....|.|.     .:|.|.:..:|:|.|.:..:..    .|||.....|.| .....:
Zfish   506 NRFSTLVGAIQKAGL-----TELLNKKGTYTFFAPTNAAFSA----LPSADLNKLMRD-PKELAN 560

  Fly   549 ILERHLAISDKEYTMKDLVKFSQESGSVILPTFRDSLSIRVEEEAGRYVIIWNYKKINVYRPDVE 613
            ||:.|:.   .|:    ||..:..|.:.:.|...|.|.:...... .||     .::.|...|:.
Zfish   561 ILKYHIG---DEF----LVSGAVTSHTRLKPLAGDKLELGTRNST-IYV-----NRVPVVESDLM 612

  Fly   614 CTNGIIHVID 623
            .|||::|.::
Zfish   613 ATNGVVHAVN 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fas1	NP_001097814.1	Fasciclin	49..159	CDD:396845	29/105 (28%)
		FAS1	215..324	CDD:214719	25/123 (20%)
		FAS1	368..476	CDD:214719	24/112 (21%)
		Fasciclin	488..627	CDD:396845	30/136 (22%)
tgfbi	NP_878282.1	Fasciclin	110..229	CDD:396845	28/103 (27%)
		Fasciclin	250..366	CDD:396845	30/144 (21%)
		Fasciclin	382..493	CDD:396845	28/135 (21%)
		FAS1	492..627	CDD:441906	35/154 (23%)