Protein Alignment Fas1 and F26E4.7

DIOPT Version :10

• Sequence 1: NP_001097814.1
• Gene: Fas1 / 42025
• FlyBaseID: FBgn0285925
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_740906.1
• Gene: F26E4.7 / 172829
• WormBaseID: WBGene00009162
• Length: 677
• Species: Caenorhabditis elegans
• Alignment Length: 637
• Identity: 161/637 - (25%)
• Similarity: 271/637 - (42%)
• Gaps: 124/637 - (19%)

  Fly    69 TIFVPTNEAF--------QRYKSKTAHVLYHITTEAYTQKRL-------PNTVSSDMAGNPPLYI 118
            |:|.|.::.|        ...|...:|::.....| .||.:|       .:|::|...     ||
 Worm    54 TVFAPVDDVFTYNPTIRAMDQKETLSHIVDSQVVE-LTQNKLWDKQTLIRSTINSGYT-----YI 112

  Fly   119 T--KNSNGDI--FVNNARIIPSLSVETNSDGKRQIMHII--DEVLEPLTVKAGHSDTPNNPNALK 177
            |  :|:.|:.  |.|...:....|   |..|      ||  ::.|..:....||...|.  .||.
 Worm   113 TQFENNPGNFSYFANAGMMCNHAS---NQWG------IISGEQYLFKICTPMGHRPYPG--TALS 166

  Fly   178 FLKN-----AEEFNVDNIGVRTYRSQVTMAKKES--VYDAA---GQHTFLVPVDEGFKLSARSSL 232
            |::.     .||...:|..:...|..:......:  :|.::   |.|||.:|.|..|......:.
 Worm   167 FIREHDGSVFEERQYNNRDLSQIRDILDRTPDIALVIYGSSAWNGFHTFFIPNDAAFARVIDRNR 231

  Fly   233 VDGKVIDGHVI-PNTVIFT-----AAAQHDDPK---ASAAFEDLLKVTV---SFFKQKNGK--MY 283
            :|.:|:..||. .|.|:||     ...||..|.   ::...||..|:.:   :...::.||  :|
 Worm   232 IDREVLLAHVTSTNRVLFTWPWLYDGGQHYYPSVRFSANIIEDNFKLKLVMRNITDRRTGKWDLY 296

  Fly   284 VKSNTIVGDAKHRVGVVLAEIVKANIPVSNGVVHLIHRPLMIIDTTVTQFLQENAENGALRKFYE 348
            ..|......::.|.|.|.|:|:..|||..|||||:|...|.|:..|:...:..|.:...|.::..
 Worm   297 AVSEVYERYSQFRRGAVWAKILVPNIPTQNGVVHIIDNVLGIVSETIDMMIYRNDKTTTLMRYIN 361

  Fly   349 VIMDNGGAVLDDINSLTE--VTILAPSNEAWN---SSNINNVLRDRNKMRQILNMHIIKDR-LNV 407
            .|    |.::.:..|.|.  ||..||.|||::   ......:||||..:.|||.:||:..: |..
 Worm   362 TI----GQIVRNYFSATGGLVTFFAPWNEAFDRIPEQIERRLLRDRIWLEQILKLHIVPAKELTS 422

  Fly   408 DKIRQKNANLIAQVPTVNNNTFLYFNVRGEGSDTVIT--VEGGGVNATVIQADVAQTNGYVHIID 470
            |:|..:..     |.||:|...||| ::||.....:|  |.|||:...::..:||.|||.||.|:
 Worm   423 DEITNETI-----VNTVDNMRQLYF-IKGEWPTNNVTYYVIGGGIKTAIMMDNVAATNGIVHYIE 481

  Fly   471 HVLGVPYTTVLGKLESDPMMSDTYKMG-----KFSHFNDQLNNTQRRFTYFVPRDKGWQKTELDY 530
            .||||||.::...:.::..:..::.|.     ::|....|:...::.||:|||.::.|.|.....
 Worm   482 RVLGVPYQSLWEIMRNESRIQASFHMMSNLQLRYSMDPWQVLTPEQNFTFFVPTNEAWHKQSTSL 546

  Fly   531 PSAHKKLFMADFSYHS--KSILERHLAISDKEYTMKDLVKFSQESGSVILPT-FRDSLSIRVEEE 592
            .:.     |.|.::..  :.:.:||:.                 .|..::.| .|:...:.:.:|
 Worm   547 VAR-----MNDGNHWQALQYVYKRHIV-----------------QGQALMYTDLRERTYVMMNDE 589

  Fly   593 AGRYVIIWNYKKINVYRP------------DVECTNGIIHVIDYPLLEEKDV 632
              :.||....:...:|.|            ::...||.:|:||..|:.|.|:
 Worm   590 --KVVIRRRGRFFELYWPRGDRRAQVLEGGEIAGINGYMHMIDSVLIYEPDL 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fas1	NP_001097814.1	Fasciclin	49..159	CDD:396845	25/110 (23%)
		FAS1	215..324	CDD:214719	37/122 (30%)
		FAS1	368..476	CDD:214719	43/113 (38%)
		Fasciclin	488..627	CDD:396845	27/158 (17%)
F26E4.7	NP_740906.1	FAS1	214..336	CDD:214719	37/121 (31%)
		Fasciclin	354..484	CDD:396845	46/139 (33%)
		FAS1	530..636	CDD:214719	24/129 (19%)